Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Modest lifestyle intervention and glucose tolerance in obese African Americans
Autore:
Racette, SB; Weiss, EP; Obert, KA; Kohrt, WM; Holloszy, JO;
Indirizzi:
Washington Univ, Sch Med, Dept Internal Med, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 nternal Med, St Louis, MO 63110 USA
Titolo Testata:
OBESITY RESEARCH
fascicolo: 6, volume: 9, anno: 2001,
pagine: 348 - 355
SICI:
1071-7323(200106)9:6<348:MLIAGT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT DIABETES-MELLITUS; PHYSICAL-ACTIVITY; WEIGHT-LOSS; INSULIN SENSITIVITY; ABDOMINAL FAT; UNITED-STATES; RISK-FACTORS; OLDER MEN; EXERCISE; WOMEN;
Keywords:
type 2 diabetes mellitus; weight loss;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Racette, SB Washington Univ, Sch Med, Dept Internal Med, Campus Box 8113,660 S Euclid Ave, St Louis, MO 63110 USA Washington Univ Campus Box 8113,660S Euclid Ave St Louis MO USA 63110
Citazione:
S.B. Racette et al., "Modest lifestyle intervention and glucose tolerance in obese African Americans", OBES RES, 9(6), 2001, pp. 348-355

Abstract

Objective: Previous studies have demonstrated the benefit of short-term diets on glucose tolerance in obese individuals. The purpose of this study was to evaluate the effectiveness of modest lifestyle changes in maintaining improvements in glucose tolerance induced by short-term energy restriction in obese African Americans with impaired glucose tolerance or type 2 diabetes mellitus. Research Methods and Procedures: An intervention group (n = 45; 47 +/- 1 year [mean +/- SE]), 105 +/- 4 kg; body mass index: 39 +/- 1 kg/m(2)) received an energy-restricted diet (943 +/- 26 kcal/d) for 1 week, followed by a lifestyle program of reduced dietary fat (-125 kcal/d) and increased physical activity (+125 kcal/d) for 1 year. Body weight and plasma concentrationsof glucose, insulin, and C-peptide during an oral glucose tolerance test were measured at baseline, 1-week, and 4-month intervals. A control group (n= 24; 48 +/- 1 year; 110 +/- 5 kg; body mass index: 41 +/- 2 kg/m2) underwent these measurements at 4-month intervals. Results: No-changes in weight or glucose tolerance were observed in the control group. The intervention group had significant (p < 0.05) improvementsin body weight and glucose tolerance in response to the 1-week diet, whichpersisted for 4 months (p < 0.001 vs. control for change in weight). A total of 19 subjects (42%) continued the intervention program for 1 year, withsustained improvements (weight: -4.6 +/- 1.0 kg; p < 0.001 vs. control; oral glucose tolerance test glucose area: -103 +/- 44 mM . min; p < 0.05 vs. control). Discussion: A modest lifestyle program facilitates weight loss and enablesimprovements in glucose tolerance to be maintained in obese individuals with abnormal glucose tolerance. However, attrition was high, despite the mild nature of the program.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:13:06