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Titolo:
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with training-induced changes in body composition: The HERITAGE Family Study
Autore:
Garenc, C; Perusse, L; Rankinen, T; Gagnon, J; Leon, AS; Skinner, JS; Wilmore, JH; Rao, DC; Bouchard, C;
Indirizzi:
Univ Laval, PEPS, Div Kinesiol, Dept Prevent Med, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 event Med, St Foy, PQ G1K 7P4, Canada Louisiana State Univ, Pennington Biomed Res Ctr, Baton Rouge, LA 70808 USALouisiana State Univ Baton Rouge LA USA 70808 , Baton Rouge, LA 70808 USA CHUQ Res Ctr, Mol Endocrinol Lab, St Foy, PQ, Canada CHUQ Res Ctr St Foy PQ Canada tr, Mol Endocrinol Lab, St Foy, PQ, Canada Univ Minnesota, Sch Kinesiol & Leisure Studies, Minneapolis, MN USA Univ Minnesota Minneapolis MN USA & Leisure Studies, Minneapolis, MN USA Indiana Univ, Dept Kinesiol, Bloomington, IN 47405 USA Indiana Univ Bloomington IN USA 47405 Kinesiol, Bloomington, IN 47405 USA Texas A&M Univ, Dept Hlth & Kinesiol, College Stn, TX USA Texas A&M Univ College Stn TX USA t Hlth & Kinesiol, College Stn, TX USA Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 Div Biostat, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Genet & Psychiat, St Louis, MO USA Washington Univ St Louis MO USA Dept Genet & Psychiat, St Louis, MO USA
Titolo Testata:
OBESITY RESEARCH
fascicolo: 6, volume: 9, anno: 2001,
pagine: 337 - 341
SICI:
1071-7323(200106)9:6<337:TTPOTB>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
INSULIN-RESISTANCE SYNDROME; BETA(3)-ADRENERGIC RECEPTOR; ADRENERGIC-RECEPTOR; DIABETES-MELLITUS; MORBID-OBESITY; TRP(64)ARG POLYMORPHISM; MASS INDEX; MUTATION; WEIGHT; METAANALYSIS;
Keywords:
beta 3-adrenergic receptor gene; Trp64Arg polymorphism; body composition; abdominal fat; endurance training;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Perusse, L Univ Laval, PEPS, Div Kinesiol, Dept Prevent Med, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 St Foy, PQ G1K 7P4, Canada
Citazione:
C. Garenc et al., "The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with training-induced changes in body composition: The HERITAGE Family Study", OBES RES, 9(6), 2001, pp. 337-341

Abstract

Objective: To investigate the association between the Trp64Arg polymorphism of the beta3-adrenergic receptor gene and changes in body composition in response to endurance training. Research Methods and Procedures: Adult sedentary white and black subjects participating in the HERITAGE Family Study were measured before and after 20 weeks on endurance training for the body mass index, fat mass, percentageof body fat, fat-free mass, sum of eight skinfolds, and subcutaneous, visceral, and total abdominal fat areas, The association between the Trp64Arg polymorphism and the response phenotypes, computed as the difference betweenpre- and post-training values, was tested by analysis of covariance separately in men and women. The gene by race interaction term was also tested. Results: No race differences were observed for allelic and genotype frequencies. Training resulted in significant reduction of body fat in both men and women. No association of the Trp64Arg polymorphism was observed with training-induced changes for any of the body composition phenotypes in both men and women. Discussion: These results suggest that the Trp64Arg polymorphism of the beta3-adrenergic receptor gene is not related to changes in body composition in response to exercise training.

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Documento generato il 07/07/20 alle ore 22:32:29