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Titolo:
Neuronal regulation of lifespan: clues from flies and worms
Autore:
Boulianne, GL;
Indirizzi:
Hosp Sick Children, Program Dev Biol, Toronto, ON M5G 1X8, Canada Hosp Sick Children Toronto ON Canada M5G 1X8 Toronto, ON M5G 1X8, Canada Univ Toronto, Dept Mol & Med Genet, Toronto, ON M5G 1X8, Canada Univ Toronto Toronto ON Canada M5G 1X8 Genet, Toronto, ON M5G 1X8, Canada Univ Toronto, Dept Zool, Toronto, ON M5G 1X8, Canada Univ Toronto TorontoON Canada M5G 1X8 Zool, Toronto, ON M5G 1X8, Canada
Titolo Testata:
MECHANISMS OF AGEING AND DEVELOPMENT
fascicolo: 9, volume: 122, anno: 2001,
pagine: 883 - 894
SICI:
0047-6374(20010715)122:9<883:NROLCF>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSGENIC DROSOPHILA-MELANOGASTER; NEMATODE CAENORHABDITIS-ELEGANS; SUPEROXIDE-DISMUTASE OVEREXPRESSION; GENE-EXPRESSION PROFILE; LONG-LIVED STRAIN; OXIDATIVE STRESS; CALORIC RESTRICTION; NERVOUS-SYSTEM; FAMILY MEMBER; MOTOR-NEURONS;
Keywords:
Drosophila; aging; lifespan; neurons;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Boulianne, GL Hosp Sick Children, Program Dev Biol, 555 Univ Ave, Toronto,ON M5G 1X8, Canada Hosp Sick Children 555 Univ Ave Toronto ON Canada M5G 1X8 da
Citazione:
G.L. Boulianne, "Neuronal regulation of lifespan: clues from flies and worms", MECH AGE D, 122(9), 2001, pp. 883-894

Abstract

Aging is a universal but poorly understood biological process that involves a complex interplay between environmental and genetic factors. Model organisms such as C. elegans and Drosophila have provided an opportunity to starch for and identify specific genes that affect life span. Interestingly, increasing evidence suggests that many of these gents affect lifespan by exerting their effects in a limited number of cell types and. in particular, neurons. indicating that the nervous system may be a central regulator of organismal lifespan. (C) 2001 Elsevier Science ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:26:06