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Titolo:
Inventory of the cytochrome P450 superfamily
Autore:
Archakov, A; Lisitsa, A; Gusev, S; Koymans, L; Janssen, P;
Indirizzi:
Inst Biomed Chem, Moscow, Russia Inst Biomed Chem Moscow RussiaInst Biomed Chem, Moscow, Russia Ctr Mol Design, Vissekaar, Belgium Ctr Mol Design Vissekaar BelgiumCtr Mol Design, Vissekaar, Belgium
Titolo Testata:
JOURNAL OF MOLECULAR MODELING
fascicolo: 5, volume: 7, anno: 2001,
pagine: 140 - 142
SICI:
1610-2940(2001)7:5<140:IOTCPS>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
NOMENCLATURE; ALIGNMENT; SEQUENCES; UPDATE;
Keywords:
inventory; cluster analysis; cytochrome P450; nomenclature;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Lisitsa, A Inst Biomed Chem, Pogodinskaya 10, Moscow, Russia Inst Biomed Chem Pogodinskaya 10 Moscow Russia Moscow, Russia
Citazione:
A. Archakov et al., "Inventory of the cytochrome P450 superfamily", J MOL MODEL, 7(5), 2001, pp. 140-142

Abstract

A non-redundant database of 325 protein sequences of the P450s has been subjected to cluster analysis. Thresholds for (sub) families have been optimized to minimize the differences between the obtained clusters and nomenclature adopted for the P450s. At the given thresholds, approximately 80% of the systematic nomenclature is reproduced by the cluster analysis. The differences primarily occur among the CYP4 and CYP6 families, which include cytochromes P450 of mammalian and insect origin. Conflicts are also encountered among plant families and among P450s of Mycobacterium tuberculosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:32:37