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Titolo:
GAP-JUNCTIONS AS ELECTRICAL SYNAPSES
Autore:
BENNETT MVL;
Indirizzi:
ALBERT EINSTEIN COLL MED,DEPT NEUROSCI BRONX NY 10461
Titolo Testata:
Journal of neurocytology
fascicolo: 6, volume: 26, anno: 1997,
pagine: 349 - 366
SICI:
0300-4864(1997)26:6<349:GAES>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
GOLDFISH MAUTHNER CELL; PROTEIN-KINASE-C; INTERCELLULAR COMMUNICATION; ELECTROTONIC SYNAPSES; HORIZONTAL CELLS; CALCIUM WAVES; NEURONS; CONDUCTANCE; VOLTAGE; DOPAMINE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
97
Recensione:
Indirizzi per estratti:
Citazione:
M.V.L. Bennett, "GAP-JUNCTIONS AS ELECTRICAL SYNAPSES", Journal of neurocytology, 26(6), 1997, pp. 349-366

Abstract

Gap junctions are the morphological substrate of one class of electrical synapse. The history of the debate on electrical vs. chemical transmission is instructive. One lesson is that Occam's razor sometimes cuts too deep; the nervous system does its operations in a number of different ways and a unitarian approach can lead one astray. Electrical synapses can do many things that chemical synapses can do, and do them just as slowly. More intriguing are the modulatory actions that chemical synapses can have on electrical synapses. Voltage dependence provides an important window on structure function relations of the connexins, even where the dependence may have no physiological role. The new molecular approaches will greatly advance our knowledge of where gap junctions occur and permit experimental manipulation with high specificity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:54:04