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Titolo:
Helicobacter pylori: a clinical update
Autore:
Moayyedi, P; Murphy, B;
Indirizzi:
Leeds Gen Infirm, Leeds LS1 3EX, W Yorkshire, England Leeds Gen Infirm Leeds W Yorkshire England LS1 3EX , W Yorkshire, England
Titolo Testata:
JOURNAL OF APPLIED MICROBIOLOGY
, volume: 90, anno: 2001, supplemento:, S
pagine: 126S - 133S
SICI:
1364-5072(2001)90:<126S:HPACU>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
OMEPRAZOLE PLUS AMOXICILLIN; RANDOMIZED CONTROLLED TRIAL; PROTON PUMP INHIBITOR; TRIPLE THERAPY; NONULCER DYSPEPSIA; DUODENAL-ULCER; GASTRIC-ULCER; ERADICATION; INFECTION; CLARITHROMYCIN;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
64
Recensione:
Indirizzi per estratti:
Indirizzo: Moayyedi, P Leeds Gen Infirm, Room 204,Clavendon Wing,Great George St, Leeds LS1 3EX, W Yorkshire, England Leeds Gen Infirm Room 204,Clavendon Wing,Great George St Leeds W Yorkshire England LS1 3EX
Citazione:
P. Moayyedi e B. Murphy, "Helicobacter pylori: a clinical update", J APPL MICR, 90, 2001, pp. 126S-133S

Abstract

The aim of the study was to summarize the indications for H. pylori therapy and the optimum regimen to use. A review of the literature revealed that H. pylori eradication therapy is indicated in peptic ulcer disease, nonulcer dyspepsia and as part of an H. pylori test and treat strategy in uninvestigated dyspepsia. The optimum therapy to use was either a proton pump inhibitor (PPI) od, clarithromycin 250 mg bd, and metronidazole 100 mg bd (PCM) or a PPI bd, clarithromycin 500 mg bd and amoxycillin 1 g bd (PAC) for 7 d. The regimen containing metronidazole is cheaper bur H. pylori may be more difficult to treat second tine if initial therapy is unsuccessful. The indications for H. pylori eradication are widening and clarithromycin containing PPI triple therapy is the treatments of choice. This review suggests two optimum therapies for H. pylori. PAC is the treatment of choice for patients with peptic ulcer disease whereas PCM may be more cost-effective for patients with non ulcer dyspepsia or uninvestigated dyspepsia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:49:55