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Titolo:
Approaches to gene therapy for human immunodeficiency virus infection
Autore:
Buchschacher, GL; Wong-Staal, F;
Indirizzi:
Univ Calif San Diego, Div Hematol Oncol, La Jolla, CA 92093 USA Univ CalifSan Diego La Jolla CA USA 92093 Oncol, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 pt Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Biol, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 t Biol, La Jolla, CA 92093 USA
Titolo Testata:
HUMAN GENE THERAPY
fascicolo: 9, volume: 12, anno: 2001,
pagine: 1013 - 1019
SICI:
1043-0342(200106)12:9<1013:ATGTFH>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; HUMAN CD34(+) CELLS; WILD-TYPE VIRUS; HU MOUSE MODEL; HUMAN T-CELLS; TOXIN-A GENE; HAIRPIN RIBOZYME; IN-VIVO; LENTIVIRAL VECTORS; HIV-1 REPLICATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
63
Recensione:
Indirizzi per estratti:
Indirizzo: Buchschacher, GL Univ Calif San Diego, Div Hematol Oncol, Stein Clin Res Bldg,Room 407,9500Gilman Dr, La Jolla, CA 92093 USA Univ Calif San Diego Stein Clin Res Bldg,Room 407,9500 Gilman Dr La Jolla CA USA 92093
Citazione:
G.L. Buchschacher e F. Wong-Staal, "Approaches to gene therapy for human immunodeficiency virus infection", HUM GENE TH, 12(9), 2001, pp. 1013-1019

Abstract

Much progress has been made in developing new and more efficient treatments for human immunodeficiency virus (HIV) infection, the cause of acquired immunodeficiency syndrome (AIDS). However, the scope of the HIV epidemic andthe limitations of existing treatments necessitate the continued development of novel treatment strategies. Gene therapy is one such forward-looking strategy. Gene therapy approaches for HIV infection include efforts to interfere with viral replication directly by engineering HIV-resistant cells orindirectly by eliminating infected cells from the body, primarily by eliciting a therapeutic immune response to destroy HIV-infected cells. Although the prospect of gene therapy as a routine treatment for HIV infection remains distant, continuous progress is being made, which should also have implications for gene therapy strategies for a variety of other diseases. This article reviews some of the strategies for investigating the feasibility of gene transfer for the treatment of HIV infection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 14:20:35