Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
In vitro evaluation of 2,4-dihydroxythiobenzanilides against various moulds
Autore:
Niewiadomy, A; Matysiak, J; Macik-Niewiadomy, G;
Indirizzi:
Univ Agr, Dept Chem, PL-20950 Lublin, Poland Univ Agr Lublin Poland PL-20950 Agr, Dept Chem, PL-20950 Lublin, Poland
Titolo Testata:
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
fascicolo: 3, volume: 13, anno: 2001,
pagine: 243 - 248
SICI:
0928-0987(200106)13:3<243:IVEO2A>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIMYCOBACTERIAL ACTIVITY; LIQUID-CHROMATOGRAPHY; TOPLISS APPROACH; THIOBENZANILIDES; COMBINATION;
Keywords:
2,4-dihydroxythiobenzanilides; anti-moulds activity; in vitro study; MIC; lipophilicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Niewiadomy, A Univ Agr, Dept Chem, Akad 15, PL-20950 Lublin, Poland Univ Agr Akad 15 Lublin Poland PL-20950 0950 Lublin, Poland
Citazione:
A. Niewiadomy et al., "In vitro evaluation of 2,4-dihydroxythiobenzanilides against various moulds", EUR J PH SC, 13(3), 2001, pp. 243-248

Abstract

The antimycotic potency of 2,4-dihydroxythiobenzanilide derivatives was tested. The MIC assessments by an agar dilution method were used for the estimation of potential activity in vitro against the four mould strains: Scopulariopsis brevicalis, Aspergillus niger, Aspergillus fumigatus and Penicillium sp. The strongest fungistatic activity was observed for 3 ' -fluoro-derivative (MIC 7.82 mug/ml). It was stated that the inhibition action of these compounds depends mainly on lipophilicity of molecules. Parabolic relationships between the antimycotic activity and lipophilicity were found. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 00:28:46