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Titolo:
Steroid hormone receptors in target cell membranes
Autore:
Pietras, RJ; Nemere, I; Szego, CM;
Indirizzi:
Univ Calif Los Angeles, Sch Med, Dept Med Hematol Oncol, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA Univ Calif Los Angeles, Sch Med, Jonsson Comprehens Canc Ctr, Los Angeles,CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles,CA 90095 USA Utah State Univ, Dept Nutr & Food Sci, Logan, UT 84322 USA Utah State Univ Logan UT USA 84322 t Nutr & Food Sci, Logan, UT 84322 USA Utah State Univ, Ctr Biotechnol, Logan, UT 84322 USA Utah State Univ Logan UT USA 84322 v, Ctr Biotechnol, Logan, UT 84322 USA Univ Calif Los Angeles, Inst Mol Biol, Dept Mol Cell & Dev Biol, Los Angeles, CA 90024 USA Univ Calif Los Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024 USA Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90024USA Univ Calif Los Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024USA
Titolo Testata:
ENDOCRINE
fascicolo: 3, volume: 14, anno: 2001,
pagine: 417 - 427
SICI:
1355-008X(200104)14:3<417:SHRITC>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-KINASE-C; MEDIATED SIGNAL PROPAGATION; ESTROGEN-BINDING PROTEINS; PLASMA-MEMBRANE; GLUCOCORTICOID RECEPTOR; THYROID-HORMONE; RAPID ACTIVATION; 1,25-DIHYDROXYVITAMIN D-3; INTRACELLULAR CALCIUM; PROGESTERONE-BINDING;
Keywords:
steroid hormone action; plasma membrane; receptor;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
113
Recensione:
Indirizzi per estratti:
Indirizzo: Pietras, RJ Univ Calif Los Angeles, Sch Med, Dept Med, Div Hematol Oncol, 11-934 Factor Bldg, Los Angeles, CA 90095 USA Univ Calif Los Angeles 11-934Factor Bldg Los Angeles CA USA 90095
Citazione:
R.J. Pietras et al., "Steroid hormone receptors in target cell membranes", ENDOCRINE, 14(3), 2001, pp. 417-427

Abstract

Numerous reports of rapid steroid hormone effects in diverse cell types cannot be explained by the generally prevailing theory that centers on the activity of hormone receptors located exclusively in the nucleus. Cell membrane forms of steroid hormone receptors coupled to intracellular signaling pathways may also play an important role in hormone action. Membrane-initiated signals appear to be the primary response of the target cell to steroid hormones and may be prerequisite to subsequent genomic activation. Recent dramatic advances in this area have intensified efforts to delineate the nature and biologic roles of all receptor molecules that function in steroid hormone-signaling pathways. This work has profound implications for our understanding of the physiology and pathophysiology of hormone actions in responsive cells and may lead to development of novel approaches for the treatment of many cell proliferative, metabolic, inflammatory, reproductive, cardiovascular, and neurologic defects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 01:46:56