Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Long-acting octreotide is effective in controlling rebleeding angiodysplasia of the gastrointestinal tract
Autore:
Orsi, P; Guatti-Zuliani, C; Okolicsanyi, L;
Indirizzi:
Univ Parma, Chair Gastroenterol, I-43100 Parma, Italy Univ Parma Parma Italy I-43100 Chair Gastroenterol, I-43100 Parma, Italy
Titolo Testata:
DIGESTIVE AND LIVER DISEASE
fascicolo: 4, volume: 33, anno: 2001,
pagine: 330 - 334
SICI:
1590-8658(200105)33:4<330:LOIEIC>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASCULAR ECTASIAS; ESTROGEN-PROGESTERONE; SOMATOSTATIN ANALOG; SMALL-INTESTINE; EFFICACY; THERAPY; MALFORMATIONS; COLON;
Keywords:
angiodysplasia; gastrointestinal bleeding; long-acting octreotide;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Okolicsanyi, L Univ Padua, Dpto Sci Chirurg & Gastroenterol Cerese, Sez Gastroenterol, Sede Treviso,Piazza Osped, I-31100 Treviso, Italy Univ Padua Sede Treviso,Piazza Osped Treviso Italy I-31100
Citazione:
P. Orsi et al., "Long-acting octreotide is effective in controlling rebleeding angiodysplasia of the gastrointestinal tract", DIG LIVER D, 33(4), 2001, pp. 330-334

Abstract

Background. Management of bleeding angiodysplasia of the gastrointestinal tract is often a major clinical problem. Lesions are frequently multiple, not detectable or missed during conventional endoscopy and patients are sometimes at high risk for complications because of advanced age and serious concomitant disorders. Aims. To determine the efficacy of a new formulation of somatostatin analogue (octreotide long-acting) in management of recurrent bleeding angiodysplasia in patients resistant to endoscopic treatment and not suitable for surgery. Patients and Methods. Three patients with recurrent bleeding angiodysplasia of gastrointestinal tract were treated with long-acting octreotide administered intramuscularly 20 mg monthly to each individual. The number of admissions for acute bleeding, hospital stay and number of blood units transfused before and after treatment (followup: 15-17 months) were regularly monitored. Results. in each patient, a relevant decrease in number of hospital admissions, duration of hospital stay, number of administered blood units was seen and mean haemoglobin values significantly increased in all of them after introducing long-acting octreotide therapyConclusions. This is the first report on use of long-acting octreotide in bleeding angiodysplasia of gastrointestinal tract. Data suggest that long-acting octreotide is a safe drug and is successful in controlling recurrent gastrointestinal bleeding due to angiodysplasia in elderly patients not elegibile for surgical or endoscopic therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 10:22:02