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Titolo:
NMDA receptor-mediated dendritic spikes and coincident signal amplification
Autore:
Schiller, J; Schiller, Y;
Indirizzi:
Technion Israel Inst Technol, Sch Med, Dept Physiol & Biophys, IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 L-31096 Haifa, Israel Rambam Med Ctr, Dept Neurol, Haifa, Israel Rambam Med Ctr Haifa IsraelRambam Med Ctr, Dept Neurol, Haifa, Israel
Titolo Testata:
CURRENT OPINION IN NEUROBIOLOGY
fascicolo: 3, volume: 11, anno: 2001,
pagine: 343 - 348
SICI:
0959-4388(200106)11:3<343:NRDSAC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CA1 PYRAMIDAL NEURONS; ACTION-POTENTIAL INITIATION; CALCIUM ACTION-POTENTIALS; APICAL DENDRITES; RAT HIPPOCAMPUS; SYNAPTIC TRANSMISSION; PLATEAU POTENTIALS; CELLULAR MECHANISM; CA2+ CHANNELS; INTEGRATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Schiller, J Technion Israel Inst Technol, Sch Med, Dept Physiol & Biophys,IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 a, Israel
Citazione:
J. Schiller e Y. Schiller, "NMDA receptor-mediated dendritic spikes and coincident signal amplification", CUR OP NEUR, 11(3), 2001, pp. 343-348

Abstract

Dendrites of cortical neurons possess active conductances, which contribute to the nonlinear processing of synaptic information. Recently it has beenshown that basal dendrites can generate highly localized spikes mediated by NMDA receptor channels. These spikes may serve as a powerful mechanism todetect and amplify synchronously activated spatially clustered excitatory synaptic inputs in individual dendritic segments, and may enable parallel processing in several integrative dendritic subunits.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:46:44