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Titolo:
Diffusion and perfusion MR imaging in acute ischemic stroke: a comparison to SPECT
Autore:
Karonen, JO; Ostergaard, L; Vainio, P; Partanen, K; Vanninen, R; Vanninen, E; Korhonen, K; Haapamaki, S; Liu, Y; Roivainen, R; Onatsu, J; Nuutinen, J; Kononen, M; Sivenius, J; Kuikka, J; Aronen, HJ;
Indirizzi:
Kuopio Univ Hosp, Dept Radiol, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 adiol, SF-70210 Kuopio, Finland Univ Helsinki, Cent Hosp, Dept Radiol, Helsinki, Finland Univ Helsinki Helsinki Finland ent Hosp, Dept Radiol, Helsinki, Finland Niuvennieuni Hosp, Dept Forens Psychiat, Kuopio, Finland Niuvennieuni Hosp Kuopio Finland Dept Forens Psychiat, Kuopio, Finland Haaga Neurol Res Ctr, Helsinki, Finland Haaga Neurol Res Ctr Helsinki Finland Neurol Res Ctr, Helsinki, Finland Aarhus Univ Hosp, Dept Neuroradiol, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 oradiol, DK-8000 Aarhus, Denmark Kuopio Univ Hosp, Dept Neurol, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 eurol, SF-70210 Kuopio, Finland Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 l Med, SF-70210 Kuopio, Finland
Titolo Testata:
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
fascicolo: 1, volume: 66, anno: 2001,
pagine: 125 - 128
SICI:
0169-2607(200107)66:1<125:DAPMII>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-RESOLUTION MEASUREMENT; TRACER BOLUS PASSAGES;
Keywords:
acute ischemic stroke; diffusion MR imaging; perfusion MR imaging; SPECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Karonen, JO Kuopio Univ Hosp, Dept Radiol, SF-70210 Kuopio, Finland KuopioUniv Hosp Kuopio Finland SF-70210 210 Kuopio, Finland
Citazione:
J.O. Karonen et al., "Diffusion and perfusion MR imaging in acute ischemic stroke: a comparison to SPECT", COMPUT M PR, 66(1), 2001, pp. 125-128

Abstract

Diffusion (DWI) and perfusion (PWI) magnetic resonance imaging are relatively new methods of clinical imaging that probably can detect infarcted (DWI) and hypoperfused but still salvageable tissue (PWI) in acute human stroke. Forty-six acute stroke patients were imaged within 24 h of ictus, on the second day and after a week. SPECT was also performed on 23 patients in theacute phase (first or second day). On the first day, mean volume of hypoperfused tissue was significantly greater (P < 0.001) than the infarcted tissue. The initial hypoperfusion volume correlated significantly with the final infarct size (P < 0.001). The initial perfusion-diffusion mismatch correlated significantly with the infarct growth (P less than or equal to 0.001). The hypoperfusion volumes measured from PWI and SPECT correlated significantly (P < 0.001). In conclusion, combined DWI and PWI is a powerful tool inevaluating the hemodynamics of acute ischemic stroke and can predict the infarct growth during 1 week. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

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Documento generato il 18/01/20 alle ore 13:10:35