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Titolo:
Does the natriuretic peptide system exist throughout the animal and plant kingdom?
Autore:
Takei, Y;
Indirizzi:
Univ Tokyo, Ocean Res Inst, Dept Marine Biosci, Div Physiol, Tokyo 1648639, Japan Univ Tokyo Tokyo Japan 1648639 Biosci, Div Physiol, Tokyo 1648639, Japan
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
fascicolo: 2-3, volume: 129, anno: 2001,
pagine: 559 - 573
SICI:
1096-4959(200106)129:2-3<559:DTNPSE>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
HAGFISH MYXINE-GLUTINOSA; AMINO-ACID-SEQUENCE; SHARK RECTAL GLAND; RELATIVE BIOLOGICAL-ACTIVITY; TROUT ONCORHYNCHUS-MYKISS; PORCINE BRAIN; MOLECULAR EVOLUTION; CARDIAC VENTRICLES; SQUALUS-ACANTHIAS; TRIAKIS-SCYLLIA;
Keywords:
atrial natriuretic peptide; comparative endocrinology; C-type natriuretic peptide; invertebrates; molecular evolution; natriuretic peptide receptors; plants; unicellular organism;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
105
Recensione:
Indirizzi per estratti:
Indirizzo: Takei, Y Univ Tokyo, Ocean Res Inst, Dept Marine Biosci, Div Physiol, 1-15-1 Minamidai, Tokyo 1648639, Japan Univ Tokyo 1-15-1 Minamidai Tokyo Japan1648639 o 1648639, Japan
Citazione:
Y. Takei, "Does the natriuretic peptide system exist throughout the animal and plant kingdom?", COMP BIOC B, 129(2-3), 2001, pp. 559-573

Abstract

Natriuretic peptides (NPs) and their receptors have been identified in vertebrate species ranging from elasmobranchs to mammals. Atrial, brain and ventricular NP (ANP, BNP and VNP) are endocrine hormones secreted from the heart, while C-type NP (CNP) is principally a paracrine factor in the brain and periphery. In elasmobranchs, only CNP is present in the heart and brain and it functions as a circulating hormone as well as a paracrine factor. Four types of NP receptors are cloned in vertebrates. NPR-A and NPR-B are guanylyl cyclase-coupled receptors, whereas NPR-C and NPR-D have only a short cytoplasmic domain. NPs are hormones important for volume regulation in mammals, while they act more specifically for Na+ regulation in fishes. The presence of NP and its receptor has also been suggested in the most primitivevertebrate group, cyclostomes, and its molecular identification is in progress. The presence of ANP or its mRNA has been reported in the hearts and ganglia of various invertebrate species such as mollusks and arthropods using either antisera raised against mammalian ANP or rat ANP cDNA as probes. Immunoreactive ANP has also been detected in the unicellular Paramecium and in various species of plants including Metasequoia. Furthermore, the N-terminal prosegments of ANP, whose sequences are scarcely conserved even in vertebrates, have also been detected by the radioimmunoassay for human ANP prosegments in all invertebrate and plant species examined including Paramecium. Although these data are highly attractive, the current evidence is too circumstantial to be convincing that the immunoreactivity truly originates from ANP and its prosegments in such diverse organisms. The caution that hasto be exercised in identification of vertebrate hormones from phylogenetically distant organisms is discussed. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 11:48:49