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Titolo:
Somatostatins and their receptors in fish
Autore:
Lin, XW; Peter, RE;
Indirizzi:
Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E9, Canada Univ Alberta Edmonton AB Canada T6G 2E9 Sci, Edmonton, AB T6G 2E9, Canada
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
fascicolo: 2-3, volume: 129, anno: 2001,
pagine: 543 - 550
SICI:
1096-4959(200106)129:2-3<543:SATRIF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
GONADOTROPIN-RELEASING-HORMONE; TROUT ONCORHYNCHUS-MYKISS; EEL ANGUILLA-ANGUILLA; GROWTH-HORMONE; MESSENGER-RNAS; RAINBOW-TROUT; MOLECULAR-CLONING; GOLDFISH BRAIN; UROTENSIN-II; LIPID-METABOLISM;
Keywords:
fish; growth hormone; somatostatin; urotensin II; somatostatin receptor; gene expression;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Peter, RE Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E9, Canada Univ Alberta Edmonton AB Canada T6G 2E9 ton, AB T6G 2E9, Canada
Citazione:
X.W. Lin e R.E. Peter, "Somatostatins and their receptors in fish", COMP BIOC B, 129(2-3), 2001, pp. 543-550

Abstract

Somatostatin (SRIF) is a multigene family of peptides. SRIF-14 is conserved with identical primary structure in species across the vertebrates. The presence of multiple SRIF genes has been demonstrated in a number of fish species. Notably, three distinct SRIF genes have been identified in goldfish. One of these genes, which encodes [Pro(2)]SRIF-14, has also been identified in sturgeon and African lungfish, and is closely associated with the amphibian [Pro(2),Met(13)]SRIF-14 gene and mammalian cortistatin gene. The mainneuroendocrine role of SRIF-14 peptide that has been determined in fish isthe inhibition of pituitary growth hormone secretion. The functions of SRIF-14 variant or larger forms of SRIF peptide and the regulation of SRIF gene expression remain to be explored. Type one and two SRIF receptors have been identified from goldfish and type three SRIF receptor from an electric fish. Fish SRIF receptors display considerable homology to mammalian counterparts in terms of primary structure and negative coupling to adenylate cyclase. The identification of the multiple gene family of SRIF peptides and multiple types of SRIF receptors in fish opens a new avenue for the study of physiological roles of SRIF, and the molecular and cellular mechanisms of SRIF actions in fish. (C) 2001 Elsevier Science Inc. Ah rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 20:14:24