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Titolo:
Hepatocyte growth factor levels in Croatian healthy and alcoholic liver cirrhosis patients
Autore:
Antoljak, N; Topic, E; Duvnjak, M; Vrkic, N; Zuntar, I;
Indirizzi:
Univ Zagreb, Sestre Milosrdnice Hosp, Inst Clin Chem, Zagreb 10000, Croatia Univ Zagreb Zagreb Croatia 10000 , Inst Clin Chem, Zagreb 10000, Croatia Univ Zagreb, Sestre Milosrdnice Hosp, Dept Gastroenterol, Zagreb, Croatia Univ Zagreb Zagreb Croatia ce Hosp, Dept Gastroenterol, Zagreb, Croatia Univ Zagreb, Sestre Milosrdnice Hosp, Dept Hepatol, Zagreb, Croatia Univ Zagreb Zagreb Croatia osrdnice Hosp, Dept Hepatol, Zagreb, Croatia
Titolo Testata:
COLLEGIUM ANTROPOLOGICUM
fascicolo: 1, volume: 25, anno: 2001,
pagine: 341 - 348
SICI:
0350-6134(200106)25:1<341:HGFLIC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-MET PROTOONCOGENE; DISEASES; PROLIFERATION; PROGNOSIS; HEPATITIS; RECEPTOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Antoljak, N Univ Zagreb, Sestre Milosrdnice Hosp, Inst Clin Chem, Vinogradska 29, Zagreb 10000, Croatia Univ Zagreb Vinogradska 29 Zagreb Croatia 10000 0000, Croatia
Citazione:
N. Antoljak et al., "Hepatocyte growth factor levels in Croatian healthy and alcoholic liver cirrhosis patients", COLL ANTROP, 25(1), 2001, pp. 341-348

Abstract

Hepatocyte growth factor (HGF) is a most potent hepatocyte mitogen, and plays a mayor role in liver regeneration during injury. The aim of this studywas to evaluate HGF values in Croatian healthy and alcoholic liver cirrhosis patients (AC). The HGF and standard laboratory tests of liver damage were measured in 33 AC patients, and 41 healthy subjects. HGF teas measured byusing an ELISA method. The HGF levels were higher in cirrhotic patients than in healthy subjects (median value is 0.78 vs. 0.19 ng/ml, p < 0.001). Japanese study showed similar values of HGF for healthy subjects and AC subjects. The HGF values in patients depend on grade of illness. There was foundsignificant correlation between HGF and almost all standard liver damage tests. The ROC analysis showed that measuring of HGF had convincingly best accuracy than other parameters, and seems to be useful in classifying grade of illness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 14:10:33