Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Alteration in digestion and absorption of nutrients during profound acid suppression
Autore:
Evenepoel, P;
Indirizzi:
Katholieke Univ Leuven Hosp, Dept Med, Div Gastroenterol, B-3000 Louvain, Belgium Katholieke Univ Leuven Hosp Louvain Belgium B-3000 3000 Louvain, Belgium Katholieke Univ Leuven Hosp, Gastrointestinal Res Ctr, B-3000 Louvain, Belgium Katholieke Univ Leuven Hosp Louvain Belgium B-3000 3000 Louvain, Belgium
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
fascicolo: 3, volume: 15, anno: 2001,
pagine: 539 - 551
SICI:
1521-6918(200106)15:3<539:AIDAAO>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DUODENAL BACTERIAL OVERGROWTH; CALCIUM-ABSORPTION; INTESTINAL-ABSORPTION; PANCREATIC-SECRETION; OMEPRAZOLE TREATMENT; ATROPHIC GASTRITIS; CYSTIC-FIBROSIS; DIETARY-PROTEIN; BREATH TEST; HYPOCHLORHYDRIA;
Keywords:
acid suppression; digestion; absorption; nutrition;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: Evenepoel, P Katholieke Univ Leuven Hosp, Dept Med, Div Gastroenterol, B-3000 Louvain, Belgium Katholieke Univ Leuven Hosp Louvain Belgium B-3000 Belgium
Citazione:
P. Evenepoel, "Alteration in digestion and absorption of nutrients during profound acid suppression", BEST PR RES, 15(3), 2001, pp. 539-551

Abstract

Gastric acid suppression therapy has for many years been the cornerstone of the treatment of peptic disease. The availability of more potent inhibitors of gastric acid secretion and the increasing demand for maintenance therapy has renewed interest in the potential side-effects of profound and/or long-lasting therapy. This chapter focuses on the potential interference of gastric acid suppression therapy with the process of the digestion and absorption of nutrients. The theoretical mechanisms by which hypochlorhydria resulting from gastric acid suppression therapy may hamper digestion and absorption are multiple and well documented. Clinical studies evaluating the effect of gastric acid suppression therapy on the assimilation of nutrients are, on the other hand, scarce and have, moreover, yielded conflicting results. The reason for the latter may be related, at least in part, to elementsof study design, Data indicating overt malabsorption or clear deficienciesin patients on long-term gastric acid suppression therapy are currently lacking, Nevertheless, it seems prudent, while awaiting the results of additional long-term studies, regularly to monitor these patients, especially those with increased nutrient demand, poor intake or suboptimal stores.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:00:56