Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Effects of dorsal and ventral striatal lesions on delayed matching trainedwith retractable levers
Autore:
Burk, JA; Mair, RG;
Indirizzi:
Univ New Hampshire, Dept Psychol, Durham, NH 03824 USA Univ New HampshireDurham NH USA 03824 Dept Psychol, Durham, NH 03824 USA
Titolo Testata:
BEHAVIOURAL BRAIN RESEARCH
fascicolo: 1, volume: 122, anno: 2001,
pagine: 67 - 78
SICI:
0166-4328(200107)122:1<67:EODAVS>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONMATCHING-TO-SAMPLE; PYRITHIAMINE-INDUCED ENCEPHALOPATHY; INTRALAMINAR THALAMIC NUCLEI; INDUCED THIAMINE-DEFICIENCY; MEDIAL PREFRONTAL CORTEX; RATS RATTUS-NORVEGICUS; BASAL GANGLIA; COMPARATIVE NEUROPSYCHOLOGY; TOPOGRAPHICAL ORGANIZATION; EFFERENT PROJECTIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Mair, RG Univ New Hampshire, Dept Psychol, Durham, NH 03824 USA Univ New Hampshire Durham NH USA 03824 hol, Durham, NH 03824 USA
Citazione:
J.A. Burk e R.G. Mair, "Effects of dorsal and ventral striatal lesions on delayed matching trainedwith retractable levers", BEH BRA RES, 122(1), 2001, pp. 67-78

Abstract

Recent evidence has suggested that thalamic amnesia results from damage tothe intralaminar nuclei, an important source of input to striatum. To testthe hypothesis that intralaminar damage disrupts functions mediated by striatum, we studied the effects of striatal lesions on a delayed matching task known to be affected by intralaminar lesions. Rats were trained to perform the task and given one of five treatments: sham surgery or a lesion of medial or lateral caudate/putamen, nucleus accumbens, or ventral striatum. Rats with ventral striatal lesions were impaired compared to all other groups. Rats with medial caudate/putamen or nucleus accumbens lesions were impaired compared to controls. The effects of ventral striatal lesions were sufficient to account for impairments in the accuracy and latency of delayed matching responses observed in previous studies of intralaminar and medial frontal cortical lesions. The ventral striatal lesions involved portions of ventral pallidum and thus it seems likely that they affected functions mediated by the nucleus accumbens as:well as striatal areas of the tubercle. Serial reversal learning trained in the same apparatus with the same reinforcerwas unaffected by all of the lesions. These results are discussed in termsof the roles of midline thalamic nuclei and of thalamo-cortico-striatal circuits in delayed conditional discrimination tasks. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:38:58