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Titolo:
Surface biology of DNA by atomic force microscopy
Autore:
Hansma, HG;
Indirizzi:
Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA Univ Calif Santa Barbara Santa Barbara CA USA 93106 Barbara, CA 93106 USA
Titolo Testata:
ANNUAL REVIEW OF PHYSICAL CHEMISTRY
, volume: 52, anno: 2001,
pagine: 71 - 92
SICI:
0066-426X(2001)52:<71:SBODBA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLI RNA-POLYMERASE; SCANNING PROBE MICROSCOPY; DEPENDENT PROTEIN-KINASE; GENE-THERAPY; SACCHAROMYCES-CEREVISIAE; STRUCTURAL TRANSITIONS; COMPLEMENTARY STRANDS; PHOSPHOLIPID-BILAYERS; CHROMOSOME STRUCTURE; SMALL CANTILEVERS;
Keywords:
biomaterials; nanotechnology; scanning probe microscopy; SFM; SPM;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
158
Recensione:
Indirizzi per estratti:
Indirizzo: Hansma, HG Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA Univ Calif Santa Barbara Santa Barbara CA USA 93106 93106 USA
Citazione:
H.G. Hansma, "Surface biology of DNA by atomic force microscopy", ANN R PH CH, 52, 2001, pp. 71-92

Abstract

The atomic force microscope operates on surfaces. Since surfaces occupy much of the space in living organisms, surface biology is a valid and valuable form of biology that has been difficult to investigate in the past owing to a lack of good technology. Atomic force microscopy (AFM) of DNA has beenused to investigate DNA condensation for gene therapy, DNA mapping and sizing, and a few applications to cancer research and to nanotechnology. Some of the most exciting new applications for atomic force microscopy of DNA involve pulling on single DNA molecules to obtain measurements of single-molecule mechanics and thermodynamics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 00:08:55