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Titolo:
Hepatitis C in a community in Upper Egypt: I. Cross-sectional survey
Autore:
Nafeh, MA; Medhat, A; Shehata, M; Mikhail, NNH; Swifee, Y; Abdel-Hamid, M; Watts, S; Fix, AD; Strickland, GT; Anwar, W; Sallam, I;
Indirizzi:
Univ Maryland, Sch Med, Dept Epidemiol & Prevent Med, Int Hlth Program, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 lth Program, Baltimore, MD 21201 USA Assiut Univ, Fac Med, Hepatitis Prevent Project C, Assuit, Egypt Assiut Univ Assuit Egypt ed, Hepatitis Prevent Project C, Assuit, Egypt Minia Univ, Fac Med, Minia, Egypt Minia Univ Minia EgyptMinia Univ, Fac Med, Minia, Egypt Amer Univ Cairo, Cairo, Egypt Amer Univ Cairo Cairo EgyptAmer Univ Cairo, Cairo, Egypt Egyptian Minist Hlth & Popolat, Cairo, Egypt Egyptian Minist Hlth & Popolat Cairo Egypt Hlth & Popolat, Cairo, Egypt
Titolo Testata:
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
fascicolo: 5-6, volume: 63, anno: 2000,
pagine: 236 - 241
SICI:
0002-9637(200011/12)63:5-6<236:HCIACI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLUNTEER BLOOD-DONORS; HIGH SEROPREVALENCE; VIRUS-INFECTION; LIVER-DISEASE; PREVALENCE; ANTIBODY; RISK; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Strickland, GT Univ Maryland, Sch Med, Dept Epidemiol & Prevent Med, Int Hlth Program, 660 W Redwood St, Baltimore, MD 21201 USA Univ Maryland 660 W Redwood St Baltimore MD USA 21201 1 USA
Citazione:
M.A. Nafeh et al., "Hepatitis C in a community in Upper Egypt: I. Cross-sectional survey", AM J TROP M, 63(5-6), 2000, pp. 236-241

Abstract

The prevalence of antibody to hepatitis C virus (anti-HCV) was determined in a cross-sectional survey in a village in Upper Egypt. Exposure and demographic characteristics were obtained through a questionnaire. Antibody to hepatitis C virus was assessed using a second generation enzyme immunoassay,and the presence of HCV RNA was tested using a reverse transcriptase - polymerase chain reaction. Collection of blood samples was targeted at those greater than or equal to 5 years old, and obtained from 62.8%. This report describes the community, the HCV infection characteristics of the subjects, and evaluates some factors associated with presence of anti-HCV. Of the 6,031 participants, 522 (8.7%) were anti-HCV positive. Prevalence was higher among males than females (11.3% versus 6.5%; P < 0.001). It was greater among those > 30 years of age than among those less than or equal to 30 years of age (20.0% versus 3.6%: P < 0.001). Those who were less educated, farmed,provided health care, and were currently married had a significantly higher anti-HCV prevalence than those who were not; however, these associations were not significant after adjusting for age. Although active infections with Schistosoma haematobium were not associated with anti-HCV, a history of pant infection was (age-adjusted risk ratio [RR] = 2.1, 95% confidence interval [CI] = 1.8, 2.4): 134 persons who had a history of receiving parenteral anti-schistosomal therapy had a higher age-adjusted RR (3.0; 95% CI = 2.5, 3.7) for anti-HCV than those who did not. Hepatitis C virus RNA was detected in 62.8% of the anti-HCV positive subjects. without significant variation by age, gender, education, or marital status. The prevalence of anti-HCVin Upper Egypt is high, albeit lower than in Lower Egypt, with continuing but limited transmission indicated by the lower prevalence in residents <less than or equal to> 30 years old.

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Documento generato il 25/01/20 alle ore 18:53:13