Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Mast cells in allergy and host defense
Autore:
Taylor, ML; Metcalfe, DD;
Indirizzi:
NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA NIAID Bethesda MD USA 20892 , Lab Allerg Dis, NIH, Bethesda, MD 20892 USA
Titolo Testata:
ALLERGY AND ASTHMA PROCEEDINGS
fascicolo: 3, volume: 22, anno: 2001,
pagine: 115 - 119
SICI:
1088-5412(200105/06)22:3<115:MCIAAH>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT MECHANISM; HISTAMINE-RELEASE; TNF-ALPHA; IMMUNITY; IGE; MICE; PHAGOCYTOSIS; MODULATION; ACTIVATION; INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Taylor, ML NIAID, Lab Allerg Dis, NIH, Bldg 10,Room 11C207,10 Ctr Dr,MSC 1881, Bethesda, MD 20892 USA NIAID Bldg 10,Room 11C207,10 Ctr Dr,MSC 1881 Bethesda MD USA 20892
Citazione:
M.L. Taylor e D.D. Metcalfe, "Mast cells in allergy and host defense", ALL ASTH P, 22(3), 2001, pp. 115-119

Abstract

Mast cells have been implicated in the pathogenesis of allergic diseases and in inflammatory responses associated with pathological immune and disease-related processes including fibrosis, autoimmune pathology, and neoplasia. Recent findings in animal models of bacterial infection also suggest thatmast cells may have a protective role in host defense against pathogens ininnate immunity along with the probable role of mast cells in acquired immunity against parasitic infections. Mast cells are strategically located atthe host-environment interface and may provide an early defense against aninvading pathogen. Mast cells express an array of adhesion and immune receptors that may assist in the recognition of invading pathogens. When activated, these cells then synthesize and release key immunoregulatory cytokines, one consequence of which is to mobilize a rapid and vigorous inflammatoryresponse. However, although it has been demonstrated that mast cells may have a role in innate immunity in defined in vitro and animal models, it remains to be determined whether mast cells are protective in innate immune responses in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/10/20 alle ore 11:22:54