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Titolo:
Association of personal and familial suicide risk with low serum cholesterol concentration in male lithium patients
Autore:
Bocchetta, A; Chillotti, C; Carboni, G; Oi, A; Ponti, M; Del Zompo, M;
Indirizzi:
Univ Cagliari, Bb Brodie Dept Neurosci, I-09124 Cagliari, Italy Univ Cagliari Cagliari Italy I-09124 t Neurosci, I-09124 Cagliari, Italy
Titolo Testata:
ACTA PSYCHIATRICA SCANDINAVICA
fascicolo: 1, volume: 104, anno: 2001,
pagine: 37 - 41
SICI:
0001-690X(200107)104:1<37:AOPAFS>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROTONIN TRANSPORTER GENE; AFFECTIVE-DISORDERS; MEN; MORTALITY; DEPRESSION; LEVEL; PREVENTION;
Keywords:
cholesterol; suicide; suicide, attempted; lithium;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Bocchetta, A Univ Cagliari, Bb Brodie Dept Neurosci, Via Porcell 4, I-09124 Cagliari, Italy Univ Cagliari Via Porcell 4 Cagliari Italy I-09124 ri, Italy
Citazione:
A. Bocchetta et al., "Association of personal and familial suicide risk with low serum cholesterol concentration in male lithium patients", ACT PSYC SC, 104(1), 2001, pp. 37-41

Abstract

Objective: We sought to establish whether low cholesterol concentration may be associated with a personal history of attempted suicide or a family history of completed suicide in psychiatric out-patients on maintenance lithium treatment, who represent a population at risk for suicide. Method: We retrospectively reviewed charts regarding 783 out-patients consecutively admitted to a lithium clinic from 1976 to 1999. Individual age- and gender-specific quartile of serum cholesterol concentration were correlated against personal lifetime suicide attempts and completed suicide in first-degree relatives. Results: The proportion of men with a personal lifetime history of attempted suicide, especially if violent, and that of men with history of completed suicide in a first-degree relative were significantly higher among the group with cholesterol concentration in the lowest quartile compared to the group with cholesterol levels above the 25th percentile. Conclusion: Low cholesterol concentration should be studied further as a potential biological/genetic marker of suicide risk.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 18:58:11