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Titolo:
Replacement of the canine inferior vena cava with a seeded graft
Autore:
Shimizu, M; Suzuki, S; Takaya, S; Satoh, K;
Indirizzi:
Hirosaki Univ, Sch Med, Inst Neurol Dis, Dept Surg 1, Hirosaki, Aomori 0368203, Japan Hirosaki Univ Hirosaki Aomori Japan 0368203 rosaki, Aomori 0368203, Japan Hirosaki Univ, Sch Med, Dept Pathol Physiol, Dept Surg 1, Hirosaki, Aomori0368203, Japan Hirosaki Univ Hirosaki Aomori Japan 0368203 irosaki, Aomori0368203, Japan
Titolo Testata:
SURGERY TODAY
fascicolo: 5, volume: 31, anno: 2001,
pagine: 421 - 427
SICI:
0941-1291(2001)31:5<421:ROTCIV>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYTETRAFLUOROETHYLENE VASCULAR GRAFTS; VENOUS OCCLUSIVE DISEASE; ENDOTHELIAL-CELLS; ADIPOSE-TISSUE; SMALL-DIAMETER; CULTURE;
Keywords:
endothelial cell seeding; centrifugal seeding method; gelatin-coated Dacron graft; inferior vena cava replacement;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Shimizu, M Hirosaki Univ, Sch Med, Inst Neurol Dis, Dept Surg 1, 5 Zaifucho, Hirosaki, Aomori 0368203, Japan Hirosaki Univ 5 Zaifucho Hirosaki AomoriJapan 0368203 3, Japan
Citazione:
M. Shimizu et al., "Replacement of the canine inferior vena cava with a seeded graft", SURG TODAY, 31(5), 2001, pp. 421-427

Abstract

The patency and microscopic findings of gelatin-coated Dacron grafts seeded with endothelial cells and implanted into the inferior vena cava of dogs was evaluated. A total of 25 mongrel dogs were divided into four experimental groups according to whether or not an antiplatelet agent was administered and a seeded or nonseeded graft was implanted. In the groups not given antiplatelet therapy that were implanted with a nonseeded graft, occlusion ofthe graft occurred soon after surgery. In contrast, in the majority of animals implanted with a seeded graft and given antiplatelet therapy, graft patency was evident for up to 4 weeks postoperatively. In the latter animals,scanning electron microscopy 4 weeks after surgery showed the formation ofconfluent endothelial-like cells within 5 mm from the anastomosis, as wellas insular endothelial-like cells in the central part of the graft. The simple centrifugal seeding method enables endothelial-like cells to adhere Tografts, suggesting that it may be useful in venous replacement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/01/21 alle ore 22:48:28