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Titolo:
LUNG MECHANICAL-BEHAVIOR DURING ONE-LUNG VENTILATION
Autore:
BARNAS GM; SPRUNG J; CHOI D; KAHN R;
Indirizzi:
CLEVELAND CLIN FDN,DEPT GEN ANESTHESIOL E31,9500 EUCLID AVE CLEVELANDOH 44195 UNIV MARYLAND,DEPT ANESTHESIOL BALTIMORE MD 21201 UNIV MARYLAND,DEPT PHYSIOL BALTIMORE MD 21201
Titolo Testata:
Journal of cardiothoracic and vascular anesthesia
fascicolo: 5, volume: 11, anno: 1997,
pagine: 604 - 607
SICI:
1053-0770(1997)11:5<604:LMDOV>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS SYNDROME; INDUCED PULMONARY-EDEMA; NORMAL RANGE; PRESSURE; SURFACTANT; IMPEDANCES; SYSTEM; DOG;
Keywords:
AIRWAYS; ELASTANCE; RESISTANCE; RESPIRATORY MECHANICS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
G.M. Barnas et al., "LUNG MECHANICAL-BEHAVIOR DURING ONE-LUNG VENTILATION", Journal of cardiothoracic and vascular anesthesia, 11(5), 1997, pp. 604-607

Abstract

Objective: Switching from two-lung to one-lung ventilation would be expected to have large effects on lung mechanical properties, and theseeffects may depend on tidal volume and respiratory frequency. These changes in lung mechanics with one-lung ventilation may be similar to pulmonary edema. Deteriorating lung mechanics during pulmonary edema have been attributed to a loss of ventilated lung units, Therefore, changes in lung mechanics caused by one-lung ventilation were measured andcompared with those previously seen during pulmonary edema. Design: Prospective study. Setting: Research laboratory. Interventions: After induction of anesthesia, beagle dogs' tracheas were intubated with an endotracheal tube with a bronchial blocker (Univent System Corp, Tokyo,Japan) to apply one-lung ventilation. The proper position of the bronchial blocker during one-lung ventilation was confirmed with a fiberoptic bronchoscope. Measurements and Main Results: Lung elastance (E-L) and resistance (R-L) were calculated from measurements of airway pressure, esophageal pressure, and airway flow in five anesthetized, paralyzed dogs during sinusoidal forcing at a constant mean airway pressure of 10 cmH(2)O in a wide range of breathing frequencies (0.2 to 1.0 Hz in intervals of 0.2) and tidal volumes (50, 100, 200, and to 300 mL). Measurements were made before and after the left mainstem bronchus wasoccluded with the bronchial blocker. During ventilation of both lungs, E-L and R-L depended relatively little on frequency, and both E-L and R-L were independent of tidal volume. During one-lung ventilation, E-L doubled and, at most frequencies, R-L increased; frequency dependences were not increased, and no dependence on tidal volume was observed. Conclusions: The lack of tidal volume dependence in E-L and lack of large-frequency dependence in R-L during one-lung ventilation are inconsistent with changes induced by severe pulmonary edema, Although decreases in ventilatable lung volume may contribute to increases in lung elastance, other characteristics of mechanical behavior during one-lung ventilation differ from those of pulmonary edema; therefore, other additional mechanisms must be involved in determining lung mechanical properties during severe pulmonary edema. Copyright (C) 1997 by W.B. Saunders Company.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 23:00:34