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Titolo:
Child health status, neurodevelopmental outcome, and parental satisfactionin a randomized, controlled trial of nitric oxide for persistent pulmonaryhypertension of the newborn
Autore:
Ellington, M; OReilly, D; Allred, EN; McCormick, MC; Wessel, DL; Kourembanas, S;
Indirizzi:
New York Hosp Med Ctr Queens, Dept Pediat, New York, NY USA New York Hosp Med Ctr Queens New York NY USA pt Pediat, New York, NY USA Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY USA Cornell Univ New York NY USA ill Med Coll, Dept Pediat, New York, NY USA Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Childrens Hosp, Neuroepidemiol Unit, Boston, MA 02115 USA Childrens Hosp Boston MA USA 02115 roepidemiol Unit, Boston, MA 02115 USA Harvard Univ, Sch Med, Childrens Hosp Boston, Dept Pediat,Div Newborn Med,Boston, MA USA Harvard Univ Boston MA USA n, Dept Pediat,Div Newborn Med,Boston, MA USA Harvard Univ, Sch Publ Hlth, Dept Maternal & Child Hlth, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 ernal & Child Hlth, Boston, MA 02115 USA Childrens Hosp, Dept Cardiol, Boston, MA 02115 USA Childrens Hosp Boston MA USA 02115 sp, Dept Cardiol, Boston, MA 02115 USA
Titolo Testata:
PEDIATRICS
fascicolo: 6, volume: 107, anno: 2001,
pagine: 1351 - 1356
SICI:
0031-4005(200106)107:6<1351:CHSNOA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXTRACORPOREAL MEMBRANE-OXYGENATION; SENSORINEURAL HEARING-LOSS; DEVELOPMENTAL FOLLOW-UP; FETAL CIRCULATION; 3-YEAR-OLD CHILDREN; BEHAVIOR PROBLEMS; INFANTS; SURVIVORS; CARE; AGE;
Keywords:
nitric oxide; parental satisfaction; infant development follow-up; persistent pulmonary hypertension of the newborn; outcome studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Ellington, M New York Hosp Med Ctr Queens, Dept Pediat, 56-45 Main St, Flushing, NY 11355 USA New York Hosp Med Ctr Queens 56-45 Main St Flushing NY USA 11355
Citazione:
M. Ellington et al., "Child health status, neurodevelopmental outcome, and parental satisfactionin a randomized, controlled trial of nitric oxide for persistent pulmonaryhypertension of the newborn", PEDIATRICS, 107(6), 2001, pp. 1351-1356

Abstract

Objective. To describe health and neurodevelopmental outcomes and parentalsatisfaction with hospital care among surviving intervention and control enrollees in a randomized, controlled trial of nitric oxide for persistent pulmonary hypertension of the newborn (PPHN). Methods. All surviving enrollees 1 to 4 years of age were eligible for follow-up. Outcomes were assessed by telephone using a trained interviewer andstandardized instruments. Domains assessed included parental report of specific conditions and hospital use, rating of general health, cognitive and motor development, behavior problems, temperament, and satisfaction with the hospital stay. Fisher's exact test and the Wilcoxon rank sum test assessed differences between intervention and control infants. Results. Interviews were completed on 60 of 83 survivors (72%). Eighteen families (22%) could not be located, 2 (2%) were non-English-speaking, and 3(4%) declined participation. No postdischarge deaths were ascertained. Among those interviewed, race, income, and education of parents of intervention and controls were comparable, as were entry oxygenation index, extracorporeal oxygenation utilization, and days of hospitalization. No differences were found in pulmonary, neurologic, cognitive, behavioral, or neurosensory outcomes; hospital readmission rates; or parental ratings of child's health. The overall neurologic handicap rate was 15%. The rate of hearing deficitwas 7%. The rate of significant behavioral problems was 26%. Levels of satisfaction expressed were high for each group. No differences in parental ratings were found between the 2 groups. Conclusions. No adverse health or neurodevelopmental outcomes have been observed among infants treated with nitric oxide for PPHN. The parents of thecritically ill infants enrolled in our clinical trial welcomed their child's inclusion and all expressed satisfaction with the care that their child received while at a tertiary care hospital. Enrollment in either arm of this randomized, controlled trial did not seem to affect parental satisfactionwith the hospital care that their child received.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 14:28:44