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Titolo:
Contribution of residential exposures to asthma in US children and adolescents
Autore:
Lanphear, BP; Kahn, RS; Berger, O; Auinger, P; Bortnick, SM; Nahhas, RW;
Indirizzi:
Childrens Hosp, Med Ctr, Cincinnati, OH 45229 USA Childrens Hosp Cincinnati OH USA 45229 Med Ctr, Cincinnati, OH 45229 USA Univ Rochester, Sch Med, Dept Pediat, Rochester, NY 14642 USA Univ Rochester Rochester NY USA 14642 ept Pediat, Rochester, NY 14642 USA Battelle Mem Inst, Columbus, OH 43201 USA Battelle Mem Inst Columbus OH USA 43201 Mem Inst, Columbus, OH 43201 USA
Titolo Testata:
PEDIATRICS
fascicolo: 6, volume: 107, anno: 2001,
pagine: NIL_73 - NIL_79
SICI:
0031-4005(200106)107:6<NIL_73:CORETA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
INNER-CITY CHILDREN; CHILDHOOD ASTHMA; RISK-FACTORS; BRONCHIAL HYPERRESPONSIVENESS; RESPIRATORY SYMPTOMS; ALLERGEN EXPOSURE; INDOOR ALLERGENS; PARENTAL SMOKING; NATIONAL SURVEY; SENSITIZATION;
Keywords:
asthma; National Health and Nutrition Examination Survey; children; pediatric; prevention; epidemiology; allergic rhinitis; housing; pets and environment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Lanphear, BP Childrens Hosp, Med Ctr, 3333 Burnet Ave, Cincinnati, OH 45229 USA Childrens Hosp 3333 Burnet Ave Cincinnati OH USA 45229 29 USA
Citazione:
B.P. Lanphear et al., "Contribution of residential exposures to asthma in US children and adolescents", PEDIATRICS, 107(6), 2001, pp. NIL_73-NIL_79

Abstract

Context. Residential exposures are recognized risk factors for asthma, butthe relative contribution of specific indoor allergens and their overall contribution to asthma among older children and adolescents in the United States are unknown. Objective. To estimate the relative contributions, population-attributablerisks, and costs of residential risk factors for doctor-diagnosed asthma. Design. Nationally representative, cross-sectional survey conducted from 1988 to 1994. Setting and Participants. A total of 5384 children who were 6 to 16 years old and participated in the National Health and Nutrition Examination Survey III, a survey of the health and nutritional status of children and adultsin the United States. Main Outcome Measure. Doctor-diagnosed asthma, as reported by the parent. Results. Five hundred three of 5384 children and adolescents (11.4%) had doctor-diagnosed asthma. After adjusting for age, gender, race, urban status, region of country, educational attainment of the head of household, and poverty, predictors of doctor-diagnosed asthma included a history of allergyto a pet (odds ratio [OR: 2.4; 95% confidence interval [CI]: 1.7, 3.3), presence of a pet in the household (OR: 1.5; 95% CI: 1.1, 2.1), and immediatehypersensitivity to dust mite (OR: 1.5; 95% CI: 1.05, 2.0), Alternaria (OR: 1.9; 95% CI: 1.3, 2.8), and cockroach allergens (OR: 1.4; CI: 1.04, 1.9). Family history of atopy (OR: 1.7; 95% CI: 1.1, 2.7) and diagnosis of allergic rhinitis (OR: 2.1; CI: 1.1, 3.7) were also predictors for asthma. The population-attributable risk of having 1 or more residential exposures associated with doctor-diagnosed asthma was 44.4% (95% CI: 29-60), or an estimated 2 million excess cases. The attributable cost of asthma resulting from residential exposures was $405 million (95% CI: $264-$547 million) annually. Conclusions. The elimination of identified residential exposures, if causally associated with asthma, would result in a 44% decline in doctor-diagnosed asthma among older children and adolescents in the United States.

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Documento generato il 05/04/20 alle ore 19:01:42