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Titolo:
Sex differences in disease anorexia
Autore:
Geary, N;
Indirizzi:
Cornell Univ, Weill Med Coll, Presbyterian Hosp, Dept Psychiat,EW Bourne Lab,Westchester Div, White Plains, NY 10605 USA Cornell Univ White Plains NY USA 10605 er Div, White Plains, NY 10605 USA
Titolo Testata:
NUTRITION
fascicolo: 6, volume: 17, anno: 2001,
pagine: 499 - 507
SICI:
0899-9007(200106)17:6<499:SDIDA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; ESTROGEN-RECEPTOR-ALPHA; TUMOR-NECROSIS-FACTOR; FOOD-INTAKE; CROHNS-DISEASE; MEDROXYPROGESTERONE ACETATE; HORMONAL INFLUENCES; ORAL CONTRACEPTION; GENDER DIFFERENCES; MEGESTROL-ACETATE;
Keywords:
food intake; feeding; acute-phase response; immune system; lipopolysaccharide; cytokines; interleukin; septic shock; Leydig-cell tumor; sarcoma; taste aversion; inflammation; gonadal steroids; estradiol; testosterone; progesterone;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
92
Recensione:
Indirizzi per estratti:
Indirizzo: Geary, N Cornell Univ, Weill Med Coll, Presbyterian Hosp, Dept Psychiat,EWBourne Lab,Westchester Div, 21 Bloomingdale Rd, White Plains, NY 10605 USACornell Univ 21 Bloomingdale Rd White Plains NY USA 10605 605 USA
Citazione:
N. Geary, "Sex differences in disease anorexia", NUTRITION, 17(6), 2001, pp. 499-507

Abstract

Sexually differentiated responses occur in molecular, cellular, physiologic, and organismic aspects of immune-system function in relation to acquiredand innate immunities. These sex differences apparently include activational effects, which depend on gonadal hormone levels in adults, and lifelong effects, which arise directly from genetic differences or organizational effects of gonadal hormones early in development that lead to lifelong sex differences. Sex differences in immune function also can have great biological significance. Despite this, the mechanisms of these effects rarely have been analyzed extensively. This is especially true of anorexia during illness or disease. Therefore, this review briefly considers 1) the biological mechanisms of sex differences; 2) sex differences in immune function; 3) clinical and experimental data related to sex differences in four diseases or disease models that involve anorexia, Crohn's inflammatory-bowel disease, cancer, turpentine inflammation, and lipopolysaccharide bacteremia; and 4) sex differences in anorexia after interleukin-l administration. (C) Elsevier Science Inc. 2001.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 19:28:49