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Titolo:
Expression of NeuroD and TrkB in developing and aged mouse olfactory epithelium
Autore:
Nibu, K; Kondo, K; Ohta, Y; Ishibashi, T; Rothstein, JL; Kaga, K;
Indirizzi:
Univ Tokyo, Grad Sch Med, Dept Otolaryngol Head & Neck Surg, Bunkyo Ku, Tokyo, Japan Univ Tokyo Tokyo Japan ryngol Head & Neck Surg, Bunkyo Ku, Tokyo, Japan Jichi Med Sch, Dept Otolaryngol, Minami Kawachi, Tochigi 32904, Japan Jichi Med Sch Minami Kawachi Tochigi Japan 32904 hi, Tochigi 32904, Japan Thomas Jefferson Univ, Jefferson Med Coll, Dept Otolaryngol Head & Neck Surg, Philadelphia, PA 19107 USA Thomas Jefferson Univ Philadelphia PA USA 19107 hiladelphia, PA 19107 USA
Titolo Testata:
NEUROREPORT
fascicolo: 8, volume: 12, anno: 2001,
pagine: 1615 - 1619
SICI:
0959-4965(20010613)12:8<1615:EONATI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
STEM-CELL; DIFFERENTIATION; MYOGENESIS; MUSCLE; MYOD;
Keywords:
BrdU; NeuroD; neurogenesis; olfactoiy neuroepithelium; TrkB;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Nibu, K Univ Tokyo, Grad Sch Med, Dept Otolaryngol Head & Neck Surg, Bunkyo Ku, Hongo 7-3-1, Tokyo, Japan Univ Tokyo Hongo 7-3-1 Tokyo Japan Ku, Hongo 7-3-1, Tokyo, Japan
Citazione:
K. Nibu et al., "Expression of NeuroD and TrkB in developing and aged mouse olfactory epithelium", NEUROREPORT, 12(8), 2001, pp. 1615-1619

Abstract

To better understand the roles of NeuroD, a member of the basic helix-loop-helix transcription factor family, during the differentiation of olfactoryreceptor neurons, we studied the expression of NeuroD in developing and aging mouse olfactory epithelium (OE). During embryonic period, NeuroD expression is confined in the basal compartment of OE. During neonatal period, NeuroD expression is detected in the middle compartment and in the basal compartment of OE. In the adult, the number of NeuroD expressing cells in the basal compartment Significantly decreased, while the NeuroD-positive cells in the middle compartment was maintained throughout lifetime. This dual phase expression pattern of NeuroD suggests multiple roles of NeuroD in the neurogenesis of ORNs; NeuroReport 12:1615-1619 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/10/20 alle ore 05:05:14