Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Salvage radiotherapy for PSA failure after radical prostatectomy
Autore:
Parker, C; Warde, P; Catton, C;
Indirizzi:
Princess Margaret Hosp, Dept Radiat Oncol, Toronto, ON M5G 2M9, Canada Princess Margaret Hosp Toronto ON Canada M5G 2M9 onto, ON M5G 2M9, Canada
Titolo Testata:
RADIOTHERAPY AND ONCOLOGY
fascicolo: 2, volume: 61, anno: 2001,
pagine: 107 - 116
SICI:
0167-8140(200111)61:2<107:SRFPFA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADJUVANT RADIATION-THERAPY; 3-DIMENSIONAL CONFORMAL RADIOTHERAPY; LOCAL RECURRENCE; ANTIGEN LEVELS; RETROPUBIC PROSTATECTOMY; ISOLATED ELEVATION; POSTPROSTATECTOMY RADIOTHERAPY; CANCER RECURRENCE; CLINICAL FAILURES; SURGICAL MARGINS;
Keywords:
radiotherapy; prostatic neoplasms; biochemical recurrence; review;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Parker, C Princess Margaret Hosp, Dept Radiat Oncol, 620 Univ Ave, Toronto, ON M5G 2M9, Canada Princess Margaret Hosp 620 Univ Ave Toronto ON Canada M5G 2M9 da
Citazione:
C. Parker et al., "Salvage radiotherapy for PSA failure after radical prostatectomy", RADIOTH ONC, 61(2), 2001, pp. 107-116

Abstract

Background and purpose: Prostate-specific antigen (PSA) failure after radical prostatectomy is a common clinical scenario, and there is no consensus on how it should be managed. Salvage radiation to the prostatic bed is a potentially curative treatment option, and is the subject of this review. Patient selection, and the efficacy and toxicity of treatment will be discussed, and recommendations made for current practice and future studies. Methods: An English language MEDLINE search was performed, limited to the years 1989-2000, using the MeSH headings 'prostatic neoplasms' and 'radiotherapy'. The 660 abstracts identified were reviewed, and articles concerningpatient selection for, or outcome of, postoperative radiation to the prostatic bed selected. After exclusion of articles concerning adjuvant, rather than salvage, radiation, this left a total of 22 case series, including 1062 patients for the review of treatment efficacy. Results and conclusions: The quality of the evidence makes it difficult toform a judgment regarding the efficacy of salvage radiation following radical prostatectomy, particularly in men with a PSA level in the range 0.01-0.2 ng/ml. Salvage radiation may be more effective,given earlier rather thanlater. These considerations have important consequences for the interpretation of current trials of adjuvant radiation following radical prostatectomy. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 10:36:15