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Titolo:
Learning and latent inhibition in old mice
Autore:
Frances, H; Tebbakha, MR; Bourre, JM;
Indirizzi:
Hop Fernand Widal, INSERM, U26, F-75475 Paris 10, France Hop Fernand Widal Paris France 10 INSERM, U26, F-75475 Paris 10, France
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 3, volume: 315, anno: 2001,
pagine: 164 - 166
SICI:
0304-3940(20011127)315:3<164:LALIIO>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELECTIVE ATTENTION; VISUAL-ATTENTION; AGE;
Keywords:
mice; aging; selective attention; latent inhibition;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Frances, H Hop Fernand Widal, INSERM, U26, 200 Rue Faubourg St Denis, F-75475 Paris 10, France Hop Fernand Widal 200 Rue Faubourg St Denis Paris France 10 ce
Citazione:
H. Frances et al., "Learning and latent inhibition in old mice", NEUROSCI L, 315(3), 2001, pp. 164-166

Abstract

The inhibitory component of selective attention has been compared in young(7-8 weeks) and older (9-10 months) female mice using the latent inhibition (LI) paradigm. LI consists of retardation in conditioning to a stimulus as a consequence of its prior non-reinforced pre-exposure. In the present work, active avoidance of an electric footshock signaled with a sound was used. Avoidances of the electric footshocks were significantly reduced in old relative to young mice which did not differ regarding pain threshold. This likely results from a slower learning in old mice. LI was significantly present and of the same importance in both young (46%) and old (49%) mice. These results suggest that in 8-9 months-old mice, the learning ability is reduced but the inhibitory component of selective attention is not altered. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:46:59