Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Voxel-based morphometry using the RAVENS maps: Methods and validation using simulated longitudinal atrophy
Autore:
Davatzikos, C; Genc, A; Xu, DR; Resnick, SM;
Indirizzi:
Johns Hopkins Univ, Sch Med, Dept Radiol, Ctr Biomed Image Comp, Baltimore, MD 21287 USA Johns Hopkins Univ Baltimore MD USA 21287 e Comp, Baltimore, MD 21287 USA NIA, Lab Personal & Cognit, NIH, Baltimore, MD 21224 USA NIA Baltimore MDUSA 21224 ersonal & Cognit, NIH, Baltimore, MD 21224 USA
Titolo Testata:
NEUROIMAGE
fascicolo: 6, volume: 14, anno: 2001,
pagine: 1361 - 1369
SICI:
1053-8119(200112)14:6<1361:VMUTRM>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN IMAGES; DEFORMABLE MODELS; REGISTRATION; DEFORMATIONS; TRANSFORMATION; INFORMATION; ATLAS; MRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Davatzikos, C Johns Hopkins Univ, Sch Med, Dept Radiol, Ctr Biomed Image Comp, 600 N Wolfe St, Baltimore, MD 21287 USA Johns Hopkins Univ 600 N WolfeSt Baltimore MD USA 21287 USA
Citazione:
C. Davatzikos et al., "Voxel-based morphometry using the RAVENS maps: Methods and validation using simulated longitudinal atrophy", NEUROIMAGE, 14(6), 2001, pp. 1361-1369

Abstract

Statistical analysis of anatomical maps in a stereotaxic space has been shown to be a useful tool in population-based studies for quantifying local anatomical differences or changes, without a priori assumptions about the location and extent of the regions of interest. This paper presents an extension and validation of a previously published methodology, referred to as RAVENS, for characterizing regional atrophy in the brain. A new method for elastic, volume-preserving spatial normalization, which allows for accurate quantification of very localized atrophy, is used. The RAVENS methodology was tested on images with simulated atrophy within two gyri: precentral and superior temporal. It was found to accurately determine the regions of atrophy, despite their localized nature and the interindividual variability of cortical structures. Moreover, it was found to perform substantially better than the voxel-based morphology method of SPM'99. Improved sensitivity was achieved at the expense of human effort involved in defining a number of sulcal curves that serve as constraints on the 3D elastic warping. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 18:04:00