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Titolo:
Prevalence of hypovitaminosis D in elderly institutionalized residents: influence of a sustitutive treatment
Autore:
Larrosa, M; Gratacos, J; Vaqueiro, M; Prat, M; Campos, F; Roque, M;
Titolo Testata:
MEDICINA CLINICA
fascicolo: 16, volume: 117, anno: 2001,
pagine: 611 - 614
SICI:
0025-7753(20011117)117:16<611:POHDIE>2.0.ZU;2-8
Fonte:
ISI
Lingua:
SPA
Soggetto:
VITAMIN-D STATUS; D SUPPLEMENTATION; HIP-FRACTURES; D DEFICIENCY; CALCIUM; WOMEN; PEOPLE; SPAIN; CALCIDIOL; SUNLIGHT;
Keywords:
vitamin D deficiency; parathyroid hormone; institutionalized residents; calcidiol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Larrosa, M Hosp Sabadell, Unidad Reumatol, Corp Parc Tauli, Parc Tauli S-N, Barcelona08208, Spain Hosp Sabadell Parc Tauli S-N Barcelona Spain 082088208, Spain
Citazione:
M. Larrosa et al., "Prevalence of hypovitaminosis D in elderly institutionalized residents: influence of a sustitutive treatment", MED CLIN, 117(16), 2001, pp. 611-614

Abstract

BACKGROUND: Osteoporosis in the elderly is a common and severe disease, vitamin D deficiency being an important causative factor. Hypovitaminosis D is frequent in old people, particularly those living in nursing homes. SUBJECTS AND METHOD: We performed a cross-sectional study of 100 randomly recruited elderly institutionalized subjects. The prevalence of hypovitaminosis D and its possible repercussion on the phosphocalcium metabolism were assessed. The degree of sun exposure and the existence of co-morbidity werealso recorded. Individuals with hypovitaminosis D were included in a longitudinal study (6 months' duration) aimed at assess the efficacy of treatment with calcium and two different therapeutic regimens with calcidiol (16,000 IU/week or 16,000 IU every 3 weeks). RESULTS: 87% of individuals had hypovitaminosis D; 21.8% of them had secondary hyperparathyroidism. The study population had a low degree of sun exposure and a high level of comorbidity. The two doses of calcidiol led to a normalization of 25-OHD3 levels, increased calciuria and compensated secondary hyperparathyroidism, yet higher 25-OHD3 levels were achieved with the weekly therapeutic scheme. CONCLUSIONS: Hypovitaminosis D prevalence appears to be very high In the elderly institutionalized population. Calcium and calcidiol supplementation normalized 25-OHD3. improved calcium absorption and compensaed secondary hyperparathyroidism. Calcium and vitamin D supplementation should be employedroutinely in the elderly institutionalized population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/08/20 alle ore 03:23:10