Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The biological function of sand fly and Leishmania glycosidases
Autore:
Jacobson, RL; Schlein, Y; Eisenberger, CL;
Indirizzi:
Hebrew Univ Jerusalem, Hadassah Med Sch, Kuvin Ctr Study Infect & trop Dis, Dept Parasitol, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel
Titolo Testata:
MEDICAL MICROBIOLOGY AND IMMUNOLOGY
fascicolo: 1-2, volume: 190, anno: 2001,
pagine: 51 - 55
SICI:
0300-8584(200111)190:1-2<51:TBFOSF>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; PHLEBOTOMUS-PAPATASI DIPTERA; LUTZOMYIA-LONGIPALPIS; HONEYDEW SUGARS; PSYCHODIDAE; SANDFLIES; CHITINASE; VECTOR; SECRETION; MOSQUITOS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Jacobson, RL Hebrew Univ Jerusalem, Hadassah Med Sch, Kuvin Ctr Study Infect & trop Dis, Dept Parasitol, POB 12272, IL-91120 Jerusalem, Israel HebrewUniv Jerusalem POB 12272 Jerusalem Israel IL-91120 el
Citazione:
R.L. Jacobson et al., "The biological function of sand fly and Leishmania glycosidases", MED MICROBI, 190(1-2), 2001, pp. 51-55

Abstract

This is a summary of the recent work on some glycosidases of sand flies and their Leishmania parasites. Glycosidases catalyze the hydrolysis of complex sugar subunits of polysaccharides into simple sugars. Leishmania major parasites secrete chitinase and N-acetylglucosaminase, which enables them tosurvive in the gut of the sand fly and are important in facilitating theirtransmission by the phlebotomine sand fly Phlebotoinus papatasi. These enzymes are found in a wide range of trypanosomatids and the gene locus is highly conserved. The sand flies feed on plants and the ingested tissues may contain cellulose particles that the sand flies are unable to digest. Cellulolytic enzymes are secreted by L. major promastigotes and this may help to break down cellulose in infected flies and sustain their growth. Starch is a main photosynthesis product that is stored in leaves. Starch grains have been found in the midguts of field caught sand flies and a-amylase, the specific enzyme for starch, has been found in the salivary glands and other organs of Lutzomyia longipalpis and P. papatasi.. oc-Amylase and Lx-glucosidase are expressed by L. major promastigotes and a-glucosidase is secreted byseveral trypanosomatid genera, but not by all those examined. Primers originally designed to amplify P. papatasi amylase DNA sequences, by polymerasechain reaction (PCR), also amplified DNA from all Old World Leishmania species, indicating that the gene is highly conserved between sand flies and these parasites.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:03:31