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Titolo:
High vegetable and fruit diet intervention in premenopausal women with cervical intraepithelial neoplasia
Autore:
Rock, CL; Moskowitz, A; Huizar, B; Saenz, CC; Clark, JT; Daly, TL; Chin, H; Beiiling, C; Ruffin, MT;
Indirizzi:
Univ Calif San Diego, Dept Family & Prevent Med, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 nt Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Reprod Med, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 od Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 Pathol, La Jolla, CA 92093 USA Innovex Inc, Parsippany, NJ USA Innovex Inc Parsippany NJ USAInnovex Inc, Parsippany, NJ USA Univ Michigan, Dept Family Med, Ann Arbor, MI 48109 USA Univ Michigan AnnArbor MI USA 48109 Family Med, Ann Arbor, MI 48109 USA
Titolo Testata:
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION
fascicolo: 10, volume: 101, anno: 2001,
pagine: 1167 - 1174
SICI:
0002-8223(200110)101:10<1167:HVAFDI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
TOTAL HOMOCYSTEINE CONCENTRATIONS; HUMAN-PAPILLOMAVIRUS INFECTION; NUTRITION EXAMINATION SURVEY; BREAST-CANCER RECURRENCE; 3RD NATIONAL-HEALTH; LIFE-STYLE FACTORS; BETA-CAROTENE; PLASMA CAROTENOIDS; RANDOMIZED TRIAL; FOLIC-ACID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Clinical Medicine
Citazioni:
54
Recensione:
Indirizzi per estratti:
Indirizzo: Rock, CL Univ Calif San Diego, Dept Family & Prevent Med, 9500 Gilman Dr, La Jolla,CA 92093 USA Univ Calif San Diego 9500 Gilman Dr La Jolla CA USA 92093 093 USA
Citazione:
C.L. Rock et al., "High vegetable and fruit diet intervention in premenopausal women with cervical intraepithelial neoplasia", J AM DIET A, 101(10), 2001, pp. 1167-1174

Abstract

Objective To examine whether diet intervention can promote increased vegetable and fruit intake, as reflected in increased plasma carotenoid and decreased plasma total homocysteine concentrations, in premenopausal women withcervical intraepithelial neoplasia, a precancerous condition. Design Randomized controlled diet intervention study. Subjects Fifty-three free-living premenopausal women who had been diagnosed with cervical intraepithelial neoplasia, were randomly assigned to an intervention (n = 27) or a control (n = 26) group. Intervention Individualized dietary counseling to increase vegetable and fruit intake. Main outcome measures Diet was assessed by food frequency questionnaire. Plasma carotenoids and total homocysteine were measured at enrollment and at6 months, follow up. Analysis Associations between baseline plasma concentrations of carotenoids and homocysteine and influencing factors were examined with multiple regression analysis. Repeated measures analysis of variance was used to test for group by time effects in these plasma concentrations. Plasma carotenoids at baseline and 6 months in the study groups, and differences in homocysteine concentrations from baseline to 6 months, were compared with independentsample t tests. Results Repeated measures analysis of variance showed significant group bytime effects (P < .01) in plasma carotenoid and homocysteine concentrations, In the intervention group, total plasma carotenoids increased by an average of 91%, from 2.04 +/- 0.13 (mean +/- standard error of the mean) Go. 3.90 +/- 0.56 mu mol/L and plasma total homocysteine was reduced by 11%, from9.01 +/- 0.40 to 8.10 +/- 0.44 mu mol/L (P < .003). Neither changed significantly in the control group. Applications Individualized dietary counseling can effectively promote increased vegetable and fruit intake in premenopausal women. This dietary pattern may reduce risk for cancer and other chronic diseases and also promote an improvement in folate status.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:30:29