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Titolo:
THE APPLICATION OF NEUROIMAGING TECHNIQUES TO DRUG DEVELOPMENT
Autore:
TAMMINGA CA; CONLEY RR;
Indirizzi:
UNIV MARYLAND,SCH MED,MARYLAND PSYCHIAT RES CTR,MAPLE & LOCUST ST,SPRING GROVE HOSP GROUNDS BALTIMORE MD 21228
Titolo Testata:
The Journal of clinical psychiatry
, volume: 58, anno: 1997, supplemento:, 10
pagine: 3 - 6
SICI:
0160-6689(1997)58:<3:TAONTT>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; C-11 N-METHYLSPIPERONE; DOPAMINE-RECEPTORS; SCHIZOPHRENIC-PATIENTS; PET; OCCUPANCY; CLOZAPINE; D-2; PSYCHOSIS; DENSITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
C.A. Tamminga e R.R. Conley, "THE APPLICATION OF NEUROIMAGING TECHNIQUES TO DRUG DEVELOPMENT", The Journal of clinical psychiatry, 58, 1997, pp. 3-6

Abstract

Neuroimaging is a powerful and innovative tool for studying the pathology of psychiatric diseases and, more recently, for studying the drugs used in their treatment. Technological advances in imaging have madeit possible to noninvasively extract information from the human brainregarding a drug's mechanism and site of action. Until now, our understanding of human brain pharmacology has depended primarily on indirect assessments or models derived from animal studies. However, the advent of multiple techniques for human brain imaging allows researchers to focus directly on human pharmacology and brain function. This reviewoutlines available neuroimaging techniques and examines how these various methods have already been applied to the drug development process, as well as how they might be applied in the future.

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Documento generato il 18/01/20 alle ore 11:09:43