Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Slow breathing reduces chemoreflex response to hypoxia and hypercapnia, and increases baroreflex sensitivity
Autore:
Bernardi, L; Gabutti, A; Porta, C; Spicuzza, L;
Indirizzi:
Univ Pavia, IRCCS, Osped S Matteo, Med Clin 1, I-27100 Pavia, Italy Univ Pavia Pavia Italy I-27100 Matteo, Med Clin 1, I-27100 Pavia, Italy Univ Pavia, Dept Internal Med, Pavia, Italy Univ Pavia Pavia ItalyUniv Pavia, Dept Internal Med, Pavia, Italy Univ Catania, Inst Resp Dis, Catania, Italy Univ Catania Catania ItalyUniv Catania, Inst Resp Dis, Catania, Italy
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 12, volume: 19, anno: 2001,
pagine: 2221 - 2229
SICI:
0263-6352(200112)19:12<2221:SBRCRT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC HEART-FAILURE; SYMPATHETIC-NERVE ACTIVITY; OBSTRUCTIVE SLEEP-APNEA; PERIPHERAL CHEMOREFLEX; VENTILATORY RESPONSES; RESPIRATORY-PATTERN; SPECTRAL-ANALYSIS; RATE-VARIABILITY; REFLEX CONTROL; BARORECEPTOR;
Keywords:
chemoreflex; baroreflex; hypoxia; hypercapnia; breathing rate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Bernardi, L Univ Pavia, IRCCS, Osped S Matteo, Med Clin 1, I-27100 Pavia, Italy Univ Pavia Pavia Italy I-27100 Clin 1, I-27100 Pavia, Italy
Citazione:
L. Bernardi et al., "Slow breathing reduces chemoreflex response to hypoxia and hypercapnia, and increases baroreflex sensitivity", J HYPERTENS, 19(12), 2001, pp. 2221-2229

Abstract

Objective To investigate whether breathing more slowly modifies the sensitivity of the chemoreflex and baroreflex. Design Setting: University of Pavia, IRCCS Policlinico S. Matteo. Participants: Fifteen healthy individuals. Interventions: Progressive isocapnic hypoxia and progressive hyperoxic hypercapnia were measured during spontaneousbreathing and during a breathing rate fixed at 6 and 15 breaths per minute(b.p.m.). Main outcome measures: Variations in chemo- and baroreflex sensitivity (by monitoring ventilation, oxygen saturation, end-tidal carbon dioxide, R-R interval and blood pressure) induced by different breathing rates. Results Breathing at 6 b.p.m. depressed (P < 0.01) both hypoxic and hypercapnic chemoreflex responses, compared with spontaneous or 15 b.p.m. controlled breathing. Hypoxic and hypercapnic responses during spontaneous breathing correlated with baseline spontaneous breathing rate (r = -0.52 and r = +0.51, respectively; P = 0.05). Baroreflex sensitivity was greater (P < 0.05) during slow breathing at baseline and remained greater at end rebreathing. Conclusions Slow breathing reduces the chemoreflex response to both hypoxia and hypercapnia. Enhanced baroreflex sensitivity might be one factor inhibiting the chemoreflex during slow breathing. A slowing breathing rate may be of benefit in conditions such as chronic heart failure that are associated with inappropriate chemoreflex activation. J Hypertens 19:2221-2229 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 09:26:47