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Titolo:
Epinephrine absorption in adults: Intramuscular versus subcutaneous injection
Autore:
Estelle, F; Simons, R; Gu, XC; Simons, KJ;
Indirizzi:
Univ Manitoba, Fac Med, Dept Pediat & Child Hlth, Allergy & Clin Immunol Sect, Winnipeg, MB, Canada Univ Manitoba Winnipeg MB Canada Clin Immunol Sect, Winnipeg, MB, Canada Univ Manitoba, Fac Pharm, Div Pharmaceut Sci, Winnipeg, MB R3T 2N2, CanadaUniv Manitoba Winnipeg MB Canada R3T 2N2 ci, Winnipeg, MB R3T 2N2, Canada
Titolo Testata:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
fascicolo: 5, volume: 108, anno: 2001,
pagine: 871 - 873
SICI:
0091-6749(200111)108:5<871:EAIAIV>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANAPHYLAXIS;
Keywords:
epinephrine; adrenaline; EpiPen; systemic anaphylaxis; anaphylactic shock; acute allergic reaction; adult; intramuscular; subcutaneous;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Simons, KJ Childrens Hosp Winnipeg, 820 Sherbrook St, Winnipeg, MB R3A 1R9, Canada Childrens Hosp Winnipeg 820 Sherbrook St Winnipeg MB Canada R3A 1R9
Citazione:
F. Estelle et al., "Epinephrine absorption in adults: Intramuscular versus subcutaneous injection", J ALLERG CL, 108(5), 2001, pp. 871-873

Abstract

We report a prospective, randomized, blinded, placebo-controlled, 6-way crossover study of intramuscular versus subcutaneous injection of epinephrinein young men. Peak plasma epinephrine concentrations were significantly higher (P < .01) after epinephrine was injected intramuscularly into the thigh than after epinephrine was injected intramuscularly or subcutaneously into the upper arm. We recommend intramuscular injection of epinephrine into the thigh as the preferred route and site of injection of this life-saving medication in the initial treatment of anaphylaxis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 16:18:00