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Titolo:
Gastrointestinal toxicity associated with nonsteroidal anti-inflammatory drugs - Epidemiologic and economic issues
Autore:
Straus, WL; Ofman, JJ;
Indirizzi:
Merck & Co Inc, Outcomes Res & Management, W Point, PA 19486 USA Merck & Co Inc W Point PA USA 19486 s & Management, W Point, PA 19486 USA Univ Penn, Sch Med, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 & Biostat, Philadelphia, PA 19104 USA Cedars Sinai Hlth Syst, Dept Med, Div Gastroenterol, Los Angeles, CA USA Cedars Sinai Hlth Syst Los Angeles CA USA roenterol, Los Angeles, CA USA Cedars Sinai Hlth Syst, Dept Hlth Serv Res, Los Angeles, CA USA Cedars Sinai Hlth Syst Los Angeles CA USA Serv Res, Los Angeles, CA USA Zynx Hlth Inc, Los Angeles, CA USA Zynx Hlth Inc Los Angeles CA USAZynx Hlth Inc, Los Angeles, CA USA
Titolo Testata:
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
fascicolo: 4, volume: 30, anno: 2001,
pagine: 895 -
SICI:
0889-8553(200112)30:4<895:GTAWNA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEPTIC-ULCER DISEASE; RANDOMIZED CONTROLLED TRIAL; ANTIINFLAMMATORY DRUGS; RHEUMATOID-ARTHRITIS; COST-EFFECTIVENESS; ELDERLY PERSONS; RISK-FACTORS; GERIATRIC PHARMACOEPIDEMIOLOGY; COLLABORATIVE METAANALYSIS; OSTEOARTHRITIS PATIENTS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
106
Recensione:
Indirizzi per estratti:
Indirizzo: Straus, WL Merck & Co Inc, Outcomes Res & Management, POB 4,WP39-160, W Point, PA 19486 USA Merck & Co Inc POB 4,WP39-160 W Point PA USA 19486 PA 19486 USA
Citazione:
W.L. Straus e J.J. Ofman, "Gastrointestinal toxicity associated with nonsteroidal anti-inflammatory drugs - Epidemiologic and economic issues", GASTRO CLIN, 30(4), 2001, pp. 895

Abstract

The large body of literature on the gastrointestinal side effects of NSAIDs has shown consistently that populations can be identified that have a markedly elevated risk for these iatrogenic conditions. These groups include the elderly, persons with prior history of peptic ulcer disease, persons receiving anticoagulant and corticosteroid therapy, and persons who require long-term NSAID therapy. It is possible that several comorbites predispose patients to gastrointestinal complications caused by NSAIDs, but few studies have adjusted carefully for the possibility that concomitant use or increased NSAID dose may account best for apparent association of comorbites as a risk factor for serious gastointestinal events.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 22:19:36