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Titolo:
The human dopamine transporter gene: gene organization, transcriptional regulation, and potential involvement in neuropsychiatric disorders
Autore:
Bannon, MJ; Michelhaugh, SK; Wang, J; Sacchetti, P;
Indirizzi:
Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 hav Neurosci, Detroit, MI 48201 USA
Titolo Testata:
EUROPEAN NEUROPSYCHOPHARMACOLOGY
fascicolo: 6, volume: 11, anno: 2001,
pagine: 449 - 455
SICI:
0924-977X(200112)11:6<449:THDTGG>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEFICIT HYPERACTIVITY DISORDER; SUBSTANTIA-NIGRA; PARKINSONS-DISEASE; NUCLEAR RECEPTORS; NGFI-B; TYROSINE-HYDROXYLASE; MESSENGER-RNAS; CODING REGION; EXPRESSION; ASSOCIATION;
Keywords:
expression; transcriptional regulation; gene polymorphisms; neuron-restrictive silencer; nurr1; variable number tandem repeat;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Bannon, MJ Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Rm 2309 Scott Hall,540 E Canfield Ave, Detroit, MI 48201 USA Wayne State Univ Rm 2309 Scott Hall,540 E Canfield Ave Detroit MI USA 48201
Citazione:
M.J. Bannon et al., "The human dopamine transporter gene: gene organization, transcriptional regulation, and potential involvement in neuropsychiatric disorders", EUR NEUROPS, 11(6), 2001, pp. 449-455

Abstract

The dopamine transporter is a plasma membrane protein that controls the spatial and temporal domains of dopamine neurotransmission through the accumulation of extracellular dopamine. The dopamine transporter may play a role in numerous dopamine-linked neuropsychiatric disorders. We review the cloning and organization of the human dopamine transporter gene, polymorphisms in its coding and noncoding sequence, and emerging data on its transcriptional regulation. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 16:51:36