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Titolo:
Lymphoscintigraphy as a result of massive malignant invasion shown by positron emission tomography
Autore:
Blocklet, D; Donckier, V; Vereecken, P; Van Geertruyden, J; Laporte, M; Goldman, S;
Indirizzi:
Free Univ Brussels, Hop Erasme, Nucl Med Serv, Dept Nucl Med, B-1070 Brussels, Belgium Free Univ Brussels Brussels Belgium B-1070 Med, B-1070 Brussels, Belgium Free Univ Brussels, Hop Erasme, Dept Surg, B-1070 Brussels, Belgium Free Univ Brussels Brussels Belgium B-1070 urg, B-1070 Brussels, Belgium Free Univ Brussels, Hop Erasme, Dept Dermatol, B-1070 Brussels, Belgium Free Univ Brussels Brussels Belgium B-1070 tol, B-1070 Brussels, Belgium Free Univ Brussels, Hop Erasme, PET Biomed Cyclotron Unit, B-1070 Brussels, Belgium Free Univ Brussels Brussels Belgium B-1070 nit, B-1070 Brussels, Belgium
Titolo Testata:
CLINICAL NUCLEAR MEDICINE
fascicolo: 12, volume: 26, anno: 2001,
pagine: 1013 - 1015
SICI:
0363-9762(200112)26:12<1013:LAAROM>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
SENTINEL NODE BIOPSY; MELANOMA PATIENTS; BREAST-CANCER; METASTASES;
Keywords:
lymphoscintigraphy; melanoma; nodal invasion; positron emission tomography; sentinel node;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Blocklet, D Free Univ Brussels, Hop Erasme, Nucl Med Serv, Dept Nucl Med, 808 Route Lennik, B-1070 Brussels, Belgium Free Univ Brussels 808 Route Lennik Brussels Belgium B-1070 m
Citazione:
D. Blocklet et al., "Lymphoscintigraphy as a result of massive malignant invasion shown by positron emission tomography", CLIN NUCL M, 26(12), 2001, pp. 1013-1015

Abstract

Purpose: The authors report the complementary roles of lymphoscintigraphy in sentinel node mapping and F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) in a massively invaded sentinel node. Materials and Methods: A 49-year-old woman was referred to the authors' institution after the resection of a malignant melanoma (Clark IV, Breslow 5.25) of the right buttock. No evidence of regional or distant organ metastases was observed on bone scintigraphy or thoracoabdominal or cerebral computed tomographs. Preoperative lymphoscintigraphy showed drainage around a circular structure, without any node detected. F-18 FDG PET imaging detected an area of focal, markedly hypermetabolic activity at the same location. Results: The focal, markedly hypermetabolic activity detected by F-18 FDG PET corresponded to a massively invaded sentinel node not shown by lymphoscintigraphy but found and removed at the time of surgery. Radical regional lymphadenectomy showed only one small additional lymph node micrometastasis detected after immunohistochemical staining for S-100 protein and HMB45 antigen. Conclusions: This case emphasizes the complementary roles of lymphoscintigraphy sentinel node mapping and F-18 FDG PET. Indeed, a massively invaded sentinel node may be detected by PET but missed by lymphoscintigraphy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 17:41:54