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Titolo:
Genetic analysis of morningness and eveningness
Autore:
Vink, JM; Groot, AS; Kerkhof, GA; Boomsma, DI;
Indirizzi:
Free Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Amsterdam Netherlands NL-1081 BT terdam, Netherlands Leiden Univ, Dept Psychol, Leiden, Netherlands Leiden Univ Leiden Netherlands Univ, Dept Psychol, Leiden, Netherlands Univ Amsterdam, Dept Psychol, Amsterdam, Netherlands Univ Amsterdam Amsterdam Netherlands pt Psychol, Amsterdam, Netherlands
Titolo Testata:
CHRONOBIOLOGY INTERNATIONAL
fascicolo: 5, volume: 18, anno: 2001,
pagine: 809 - 822
SICI:
0742-0528(2001)18:5<809:GAOMAE>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CIRCADIAN-RHYTHMS; DIURNAL PREFERENCE; POLYMORPHISM; PERIOD; SLEEP;
Keywords:
circadian rhythm; generation difference; heritability; morningness-eveningness; parent-offspring; sex difference; twins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Vink, JM Free Univ Amsterdam, Dept Biol Psychol, Van Boechorststr 1, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Van Boechorststr 1 Amsterdam Netherlands NL-1081 BT
Citazione:
J.M. Vink et al., "Genetic analysis of morningness and eveningness", CHRONOBIO I, 18(5), 2001, pp. 809-822

Abstract

We studied the influence of genetic factors on individual differences in morningness-eveningness in a sample of Dutch twin families. Data were collected from adolescent twins (mean age 17.8 yr) and their parents (mean age offathers 48.0 yr and of mothers 46.0 yr) and a sample of older twins (mean age 46.5 yr). Scores on morningness-eveningness were rated on a 5-point scale. Parents were more morning oriented than their children, and women were more morning oriented than men. With a twin-family study, separation of genetic and environmental influences on variation in morningness-eveningness is possible. Including parents and older twins in the study makes it possible to explore generation differences in these effects. The correlation between monozygotic twins was more than twice the correlation between dizygotic twins. This indicates that genetic effects may not operate in an additive manner. Therefore, a model that included genetic dominance was explored. Biometrical model fitting showed no sex differences for the magnitude of genetic and environmental factors. The total heritability-the sum of additive and nonadditive genetic influences-for morningness-eveningness was 44% for the younger generation and 47% for the older generation. How ever, the genetic correlation between the generations turned out to be lower than 0.5, suggesting that different genes for morningness-eveningness are expressed in both generations.

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Documento generato il 21/01/20 alle ore 07:06:38