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Titolo:
Regulation of hydroxyindole-O-methyltransferase gene expression in Japanese quail (Coturnix coturnix japonica)
Autore:
Fu, ZW; Kato, H; Kotera, N; Noguchi, T; Sugahara, K; Kubo, T;
Indirizzi:
Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Lab Nutr Biochem, Tokyo 1138657, Japan Univ Tokyo Tokyo Japan 1138657 m, Lab Nutr Biochem, Tokyo 1138657, Japan Utsunomiya Univ, Fac Agr, Utsunomiya, Tochigi 3218505, Japan Utsunomiya Univ Utsunomiya Tochigi Japan 3218505 , Tochigi 3218505, Japan
Titolo Testata:
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
fascicolo: 11, volume: 65, anno: 2001,
pagine: 2504 - 2511
SICI:
0916-8451(200111)65:11<2504:ROHGEI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROTONIN N-ACETYLTRANSFERASE; CHICKEN PINEAL-GLAND; VITAMIN-A-DEFICIENCY; MESSENGER-RNA LEVELS; CIRCADIAN-RHYTHMS; RAT PINEAL; PHOTOENDOCRINE TRANSDUCTION; MELATONIN SYNTHESIS; BIOLOGICAL CLOCK; BINDING-SITES;
Keywords:
hydroxyindole-O-methyltrasferase; arylalkylamine N-acetyltransferase; melatonin; vitamin A; pineal gland;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Kato, H Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Lab NutrBiochem, Tokyo 1138657, Japan Univ Tokyo Tokyo Japan 1138657 utr Biochem, Tokyo 1138657, Japan
Citazione:
Z.W. Fu et al., "Regulation of hydroxyindole-O-methyltransferase gene expression in Japanese quail (Coturnix coturnix japonica)", BIOS BIOT B, 65(11), 2001, pp. 2504-2511

Abstract

Hydroxyindole-O-methyltrasferase (HIOMT) plays an important role as the final enzyme in the synthesis of melatonin. In this study, the expression of the HIOMT gene in Japanese quail was investigated with respect to tissue distribution and the effects of light and vitamin A deficiency. HIOMT mRNA inthe pineal gland and eye had a clear daily rhythm with peak values in daytime. The testis also contained a detectable amount of HIOMT mRNA, which didnot display a rhythmic change over a 24-h period. When birds were renderedvitamin A deficient through feeding with a vitamin A-free diet, the daily rhythm of the HIOMT gene almost disappeared in both the pineal gland and eye due to increases in the nighttime values. Our previous observations and these results suggest that vitamin A and a photo-signal are required to maintain the rhythmic expression of the HIOMT gene as well as the arylalkylamine N-acetyltransferase gene.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 07:58:17