Catalogo Articoli (Spogli Riviste)

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Titolo:
Spatial structure of discoidal high density lipoproteins
Autore:
Dobretsov, GE; Dergunov, AD;
Indirizzi:
Res Inst Phys Chem Med, Moscow 119828, Russia Res Inst Phys Chem Med Moscow Russia 119828 m Med, Moscow 119828, Russia Natl Res Ctr Prevent Med, Moscow 101953, Russia Natl Res Ctr Prevent Med Moscow Russia 101953 Med, Moscow 101953, Russia
Titolo Testata:
BIOLOGICHESKIE MEMBRANY
fascicolo: 5, volume: 18, anno: 2001,
pagine: 339 - 352
SICI:
0233-4755(200109/10)18:5<339:SSODHD>2.0.ZU;2-K
Fonte:
ISI
Lingua:
RUS
Soggetto:
APOLIPOPROTEIN-A-I; LECITHIN-CHOLESTEROL-ACYLTRANSFERASE; CENTRAL ALPHA-HELICES; RECONSTITUTED LPA-I; MICELLAR COMPLEXES; ENERGY-TRANSFER; APOA-I; DIMYRISTOYL LECITHIN; CELLULAR CHOLESTEROL; PLASMA-LIPOPROTEINS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
117
Recensione:
Indirizzi per estratti:
Indirizzo: Dobretsov, GE Res Inst Phys Chem Med, Malaya Pirogovskaya Ul 1A, Moscow 119828, Russia Res Inst Phys Chem Med Malaya Pirogovskaya Ul 1A Moscow Russia 119828
Citazione:
G.E. Dobretsov e A.D. Dergunov, "Spatial structure of discoidal high density lipoproteins", BIOL MEMB, 18(5), 2001, pp. 339-352

Abstract

The paper reviews the data on spatial structure of discoidal high density lipoproteins. At present discoidal lipoproteins reconstituted in vitro fromapolipoprotein A-I and synthetic phospholipids are the most well studied. Recently many data have been obtained on the role of each domain of apoA-I molecule in the particle formation, its activation of lecithin: cholesterolacyltransferase and its interaction with cellular membranes. These resultes were obtained due to synthesis of mutant apolipoproteins A-I with different variants of primary structure. Although several alternative models of the discoidal particle were proposed, each describing some known properties of the particles, there is no an universal model. Perhaps, more effective physical methods are necessary for more detailed study of the disc structure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 06:13:53