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Titolo:
An automated synthesis module for preparation of L-3-[I-123]iodo-alpha-methyl tyrosine
Autore:
Luurtsema, G; Jager, PL; Piers, A; de Hooge, MN;
Indirizzi:
Univ Groningen Hosp, Dept Nucl Med, NL-9700 RB Groningen, Netherlands UnivGroningen Hosp Groningen Netherlands NL-9700 RB ningen, Netherlands
Titolo Testata:
APPLIED RADIATION AND ISOTOPES
fascicolo: 6, volume: 55, anno: 2001,
pagine: 783 - 788
SICI:
0969-8043(200112)55:6<783:AASMFP>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
IODINE-123-ALPHA-METHYL TYROSINE; BRAIN; TOMOGRAPHY; GLIOMAS; TUMORS;
Keywords:
iodo-alpha methyl tyrosine; automation; radiosynthesis; I-123;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Jager, PL Univ Groningen Hosp, Dept Nucl Med, POB 30001, NL-9700 RB Groningen, Netherlands Univ Groningen Hosp POB 30001 Groningen Netherlands NL-9700 RB
Citazione:
G. Luurtsema et al., "An automated synthesis module for preparation of L-3-[I-123]iodo-alpha-methyl tyrosine", APPL RAD IS, 55(6), 2001, pp. 783-788

Abstract

L-3-[I-123]iodo-alpha-methyl tyrosine (IMT) is an artificial amino acid suitable for SPECT imaging of various tumours. Manual synthesis of this radiopharmaceutical is reliable, but time-consuming and may require handling of large quantities of radioactivity. We developed an automated IMT synthesis module, which prepares a ready-to-inject product that meets radiopharmaceutical requirements and is identical to the manually synthesised equivalent. Current advantages include decreased operator assistance time and reduced radiation exposure. Application may be extended to other radio pharmaceuticals. including high-dose preparations for therapeutic use. (C). 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/01/21 alle ore 07:51:58