Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Resonance Rayleigh scattering spectra for studying the interaction of heparin with some basic phenothiazine dyes and their analytical applications
Autore:
Luo, HQ; Liu, SP; Liu, ZF; Liu, Q; Li, NB;
Indirizzi:
SW China Normal Univ, Inst Environm Chem, Chongqing 400715, Peoples R China SW China Normal Univ Chongqing Peoples R China 400715 5, Peoples R China
Titolo Testata:
ANALYTICA CHIMICA ACTA
fascicolo: 1-2, volume: 449, anno: 2001,
pagine: 261 - 270
SICI:
0003-2670(200112)449:1-2<261:RRSSFS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; LIGHT-SCATTERING; TRACE AMOUNTS; SULFATE; SYSTEMS; ASSAY; GLYCOSAMINOGLYCANS; AGGREGATION;
Keywords:
heparin; basic phenothiazine dyes; resonance Rayleigh scattering;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Liu, SP SW China Normal Univ, Inst Environm Chem, Chongqing 400715, Peoples R China SW China Normal Univ Chongqing Peoples R China 400715 es R China
Citazione:
H.Q. Luo et al., "Resonance Rayleigh scattering spectra for studying the interaction of heparin with some basic phenothiazine dyes and their analytical applications", ANALYT CHIM, 449(1-2), 2001, pp. 261-270

Abstract

In near neutral medium, binding of heparin with some basic phenothiazine dyes such as methylene blue (MB), Azure B or toluidine blue (TB) can result in a significant enhancement of resonance Rayleigh scattering (RRS) and appearance of a new RRS spectrum. Their maximum scattered wavelengths appear at 346, 338 and 329 urn for MB, Azure B and TB, respectively. The optimum conditions of these reactions, the influencing factors and the relationship between the RRS intensity and the concentration of heparin have been investigated. A new method for the determination of trace amounts of heparin basedon the RRS method has been developed. The methods exhibit high sensitivities, the detection limits for heparin are 9.0 ng ml(-1) for MB, 14.5 ng ml(-1) for Azure B and 26.0 ng ml(-1) for TB. Among them the MB is the most sensitive and has better selectivity, so it was applied to the determination of heparin in heparin sodium injection samples with satisfactory results. The mechanisms of the effect are discussed. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 23:53:55