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Titolo:
Effect of beta blockers alone, of angiotensin-converting enzyme inhibitorsalone, and of beta blockers plus angiotensin-converting enzyme inhibitors on new coronary events and on congestive heart failure in older persons with healed myocardial infarcts and asymptomatic left ventricular systolic dysfunction
Autore:
Aronow, WS; Ahn, C; Kronzon, I;
Indirizzi:
New York Med Coll, Westchester Med Ctr, Dept Med, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 Dept Med, Valhalla, NY 10595 USA NYU, Sch Med, Dept Med, New York, NY USA NYU New York NY USANYU, Sch Med, Dept Med, New York, NY USA Univ Texas, Sch Med, Div Clin Epidemiol, Houston, TX USA Univ Texas Houston TX USA , Sch Med, Div Clin Epidemiol, Houston, TX USA
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 11, volume: 88, anno: 2001,
pagine: 1298 -
SICI:
0002-9149(200112)88:11<1298:EOBBAO>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
MORTALITY; SURVIVAL; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Aronow, WS New York Med Coll, Westchester Med Ctr, Dept Med, 23 Pebble Way, New Rochelle, NY 10804 USA New York Med Coll 23 Pebble Way New Rochelle NY USA 10804 4 USA
Citazione:
W.S. Aronow et al., "Effect of beta blockers alone, of angiotensin-converting enzyme inhibitorsalone, and of beta blockers plus angiotensin-converting enzyme inhibitors on new coronary events and on congestive heart failure in older persons with healed myocardial infarcts and asymptomatic left ventricular systolic dysfunction", AM J CARD, 88(11), 2001, pp. 1298

Abstract

Of 477 asymptomatic persons, mean age 79 +/- 8 years, with prior myocardial infarction and a left ventricular ejection fraction less than or equal to40%, 107 (22%) were treated with beta blockers alone, 89 (19%) with angiotensin-converting enzyme (ACE) inhibitors alone, 132 (28%) with beta blockers plus ACE inhibitors, and 149 (31%) with no beta blocker or ACE inhibitor,and followed for 31 +/- 19 months. The Cox regression model showed that compared with treatment with no beta blocker or ACE inhibitor, the percent reduction in new coronary events was 25% for beta blockers alone, 17% for ACEinhibitors alone, and 37% for beta blockers plus ACE inhibitors; the percent reduction in congestive heart failure was 41% for beta blockers alone, 32% for ACE inhibitors alone, and 60%, for beta blockers plus ACE inhibitors.

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Documento generato il 05/04/20 alle ore 06:49:09