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Titolo:
Coronary stenting in diabetic patients: Results from the ROSETTA registry
Autore:
Huynh, T; Eisenberg, M; Deligonul, U; Tsang, J; Okrainec, K; Schechter, D; Lefkovits, J; Mak, KH; Brown, DL; Brieger, D;
Indirizzi:
McGill Univ, Montreal Gen Hosp, Div Cardiol, Montreal, PQ H3G 1A4, Canada McGill Univ Montreal PQ Canada H3G 1A4 diol, Montreal, PQ H3G 1A4, Canada McGill Univ, Jewish Gen Hosp, Montreal, PQ H3T 1E2, Canada McGill Univ Montreal PQ Canada H3T 1E2 Hosp, Montreal, PQ H3T 1E2, Canada Univ Texas, Ctr Hlth, Tyler, TX 75710 USA Univ Texas Tyler TX USA 75710Univ Texas, Ctr Hlth, Tyler, TX 75710 USA Hadassah Hebrew Univ Hosp, Jerusalem, Israel Hadassah Hebrew Univ Hosp Jerusalem Israel Univ Hosp, Jerusalem, Israel Royal Melbourne Hosp, Parkville, Vic 3050, Australia Royal Melbourne HospParkville Vic Australia 3050 le, Vic 3050, Australia Concord Hosp, Sydney, NSW, Australia Concord Hosp Sydney NSW AustraliaConcord Hosp, Sydney, NSW, Australia Natl Heart Ctr, Singapore, Singapore Natl Heart Ctr Singapore SingaporeNatl Heart Ctr, Singapore, Singapore Albert Einstein Coll Med, New York, NY USA Albert Einstein Coll Med New York NY USA tein Coll Med, New York, NY USA
Titolo Testata:
AMERICAN HEART JOURNAL
fascicolo: 6, volume: 142, anno: 2001,
pagine: 960 - 964
SICI:
0002-8703(200112)142:6<960:CSIDPR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SMOOTH-MUSCLE CELLS; BALLOON ANGIOPLASTY; ARTERY DISEASE; INTIMAL HYPERPLASIA; ENDOTHELIAL-CELLS; GENE-EXPRESSION; NITRIC-OXIDE; MELLITUS; RESTENOSIS; IMPLANTATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Huynh, T McGill Univ, Montreal Gen Hosp, Div Cardiol, 1650 Cedar,Room E5-200, Montreal, PQ H3G 1A4, Canada McGill Univ 1650 Cedar,Room E5-200 Montreal PQ Canada H3G 1A4 ada
Citazione:
T. Huynh et al., "Coronary stenting in diabetic patients: Results from the ROSETTA registry", AM HEART J, 142(6), 2001, pp. 960-964

Abstract

Objective Diabetes mellitus is associated with high rates of restenosis and adverse outcomes after percutaneous transluminal coronary angioplasty (PTCA). It is unclear whether coronary stenting reduces adverse events in diabetic patients after PTCA. Our purpose was to determine whether coronary stenting improves clinical event rates in diabetic patients after PTCA. Methods The Routine Versus Selective Exercise Treadmill Testing After Angioplasty (ROSETTA) registry was a prospective multicenter observational study examining functional testing and adverse outcomes after successful PTCA. Results: Among the 791 patients enrolled, 180 were diabetic. A total of 90diabetics received stents while the remaining 90 patients did not. Baseline clinical characteristics were similar between the 2 groups of patients. However, patients with stents were more likely to have complex lesions, whereas those without stents were more likely to undergo atherectomy and cave greater residual coronary stenosis. At 6-month follow-up, the composite end:point defined as cardiac death, unstable angina, myocardial infarction, need for repeat PTCA, or coronary artery bypass graft surgery (CABG) occurredin 25.0% of stented and 22.2% of nonstented diabetic patients (P not significant [NS]). A multivariate logistic regression analysis showed that coronary stenting was not associated with a reduced incidence of the composite end point among diabetic patients (odds ratio 0.97, 95% Cl 0.46-2.05, P NS). Conclusion Coronary stenting does not improve clinical event rates in diabetic patients after PTCA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 02:07:25