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Titolo:
Update on gene and immune based therapy for urologic malignancy
Autore:
Wieder, J; Freedland, SJ; Pantuck, AJ; Zisman, A; Belldegrun, AS;
Indirizzi:
Univ Calif Los Angeles, Sch Med, Dept Urol, Div Urol Oncol, Los Angeles, CA 90024 USA Univ Calif Los Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024 USA
Titolo Testata:
UROLOGIC ONCOLOGY
fascicolo: 6, volume: 6, anno: 2001,
pagine: 265 - 275
SICI:
1078-1439(200111/12)6:6<265:UOGAIB>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROSTATE-SPECIFIC ANTIGEN; RENAL-CELL CARCINOMA; HUMAN BLADDER-CANCER; TUMOR-SUPPRESSOR GENE; HUMAN DENDRITIC CELLS; DNA/DMRIE/DOPE LIPID COMPLEX; TISSUE-SPECIFIC EXPRESSION; VIRUS THYMIDINE-KINASE; VON-HIPPEL-LINDAU; I CLINICAL-TRIAL;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
120
Recensione:
Indirizzi per estratti:
Indirizzo: Belldegrun, AS Univ Calif Los Angeles, Sch Med, Dept Urol, Div Urol Oncol,Los Angeles, CA 90024 USA Univ Calif Los Angeles Los Angeles CA USA 90024 90024 USA
Citazione:
J. Wieder et al., "Update on gene and immune based therapy for urologic malignancy", UROL ONCOL, 6(6), 2001, pp. 265-275

Abstract

The discovery of genes involved in malignant transformation and tumor growth has lead to the development of anti-cancer gene therapies. In addition, new modifications to immune based therapy have recently been developed. In this review, we focus on modern genetic and immunologic approaches to the treatment of urologic malignancy. We summarize new developments in vectors, tumor suppressors, suicide genes, gene based immunotherapy, tumor vaccines,dendritic cell therapy, and graft vs. tumor therapy. Additional topics described include prostate antigens and prostate specific promoters. Pre-clinical and clinical trials that utilize these therapies are summarized. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:38:30