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Titolo:
Ruling out myocardial infarction with troponin T and creatine kinase MB mass: Diagnostic and prognostic aspects
Autore:
Koukkunen, H; Penttila, K; Kemppainen, A; Penttila, K; Halinen, M; Rantanen, T; Pyorala, K;
Indirizzi:
Kuopio Univ Hosp, Dept Med, FI-70211 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FI-70211 t Med, FI-70211 Kuopio, Finland Kuopio Univ Hosp, Dept Clin Chem, FI-70211 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FI-70211 Chem, FI-70211 Kuopio, Finland Univ Turku, Cent Hosp, Dept Med, FIN-20520 Turku, Finland Univ Turku Turku Finland FIN-20520 p, Dept Med, FIN-20520 Turku, Finland Kuopio Univ Hosp, Dept Accid & Emergency, FI-70211 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FI-70211 gency, FI-70211 Kuopio, Finland
Titolo Testata:
SCANDINAVIAN CARDIOVASCULAR JOURNAL
fascicolo: 5, volume: 35, anno: 2001,
pagine: 302 - 306
SICI:
1401-7431(200110)35:5<302:ROMIWT>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE CHEST PAIN; EMERGENCY ROOM; MYOGLOBIN; DISCHARGE; MARKERS; HEART;
Keywords:
CK-MB mass; FINMONICA; myocardial infarction; troponin T;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Koukkunen, H Kuopio Univ Hosp, Dept Med, POB 1777, FI-70211 Kuopio, Finland Kuopio Univ Hosp POB 1777 Kuopio Finland FI-70211 o, Finland
Citazione:
H. Koukkunen et al., "Ruling out myocardial infarction with troponin T and creatine kinase MB mass: Diagnostic and prognostic aspects", SC CARDIOVA, 35(5), 2001, pp. 302-306

Abstract

Objective-To investigate the time window for ruling out myocardial infarction (MI) with troponin T (TnT) and creatine kinase isoenzyme MB mass (CK-MBm) and the prognosis of patients with ruled-out MI diagnosis. Design-The study was based on 397 patients admitted with a suspected acutecoronary syndrome but with relief of symptoms within 24 h. Results-MI diagnosis was confirmed with elevated TnT (>0.10 mug/l) in 108 patients, in 91%within 12-24 h from the onset of symptoms, and in 99% within 12 It from admission. In 94 of these patients CK-MBm became elevated (>5.0 mug/l), in 95% within 10-12 h from the onset of symptoms, and in 99% within 6 h from admission. Among patients with ruled-out MI diagnosis, the 1-year incidence ofrecurrent coronary events was 29% in those with positive history of coronary heart disease (CHD) but only 7% in those without prior CHD (p < 0.001). Conclusion-Using TnT or CK-MBm, MI can be ruled out within 12 h from admission in the majority of patients. Among patients with ruled-out MI diagnosis, positive history of CHD is an important determinant of prognosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 11:51:13