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Titolo:
Oxygen saturation in adult cystic fibrosis patients during exercise at high altitude
Autore:
Ryujin, DT; Mannebach, SC; Samuelson, WM; Marshall, BC;
Indirizzi:
Utah Hlth Sci Ctr, Intermt Cyst Fibrosis Ctr, Salt Lake City, UT USA Utah Hlth Sci Ctr Salt Lake City UT USA osis Ctr, Salt Lake City, UT USA Utah Hlth Sci Ctr, Pulm Lab, Salt Lake City, UT USA Utah Hlth Sci Ctr Salt Lake City UT USA Pulm Lab, Salt Lake City, UT USA Utah Hlth Sci Ctr, Dept Med, Salt Lake City, UT USA Utah Hlth Sci Ctr Salt Lake City UT USA Dept Med, Salt Lake City, UT USA Univ Utah, Hlth Sci Ctr, Dept Pediat, Salt Lake City, UT 84132 USA Univ Utah Salt Lake City UT USA 84132 ediat, Salt Lake City, UT 84132 USA Salt Lake VA Med Ctr, Salt Lake City, UT USA Salt Lake VA Med Ctr Salt Lake City UT USA d Ctr, Salt Lake City, UT USA
Titolo Testata:
PEDIATRIC PULMONOLOGY
fascicolo: 6, volume: 32, anno: 2001,
pagine: 437 - 441
SICI:
8755-6863(200112)32:6<437:OSIACF>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPOXEMIA; CAPACITY; DESATURATION; OBSTRUCTION; SLEEP;
Keywords:
cystic fibrosis; exercise; lung function; high altitude;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Marshall, BC Univ Utah Hlth Sci, Div Pulm, 26 North 1900 East, Salt Lake City, UT 84132USA Univ Utah Hlth Sci 26 North 1900 East Salt Lake City UT USA 84132
Citazione:
D.T. Ryujin et al., "Oxygen saturation in adult cystic fibrosis patients during exercise at high altitude", PEDIAT PULM, 32(6), 2001, pp. 437-441

Abstract

The objective of this study was to determine the frequency and severity ofdecreased arterial oxy-hemoglobin saturation during exercise in adults with cystic fibrosis at 1,500 m above sea level. A convenience sample of 50 adults with cystic fibrosis who did not have hypoxemia (oxygen saturation, < 90%) at rest were evaluated. Spirometry was performed according to AmericanThoracic Society standards, and maximal exercise tests were performed on an electronically braked cycle ergometer using a ramp protocol individualized for each patient. Pulse oximetry was measured every 2 min. When exercising at high altitude, 45 of 50 patients had a decrease in arterial oxy-hemoglobin saturation from baseline to some degree. In 29 patients, oxy-hemoglobin saturation fell below 90%; in 14 patients, it fell below 85%; and in 4 patients, it fell below 80%. Oxy-hemoglobin saturation decreased to < 90% in 12 of 14 patients with severe pulmonary disease (FEV1 < 40% predicted), in 15 of 26 patients with moderate disease (40% less than or equal to FEV1 < 70% predicted), in 2 of 6 patients with mild disease (70% less than or equal to FEV, < 90% predicted), and in 0 of 4 with normal pulmonary function (FEV, greater than or equal to 90%). Percent predicted FEV1 (r=0.57; P<less than>0.0001) and FEV1/FVC ratio (r=0.52; P<0.0001) most highlycorrelated with arterial oxy-hemoglobin saturation at peak exercise. We conclude that at 1,500 m above sea level, adult CF patients with obstructive airways disease are at significant risk for decreased arterial oxy-hemoglobin saturation during exercise. A supervised exercise test should be considered prior to recommending an exercise program for such patients. <(c)> 2001Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 10:47:04