Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Novel synthetic approach to 19-nor-1 alpha,25-dihydroxyvitamin D-3 and itsderivatives by Suzuki-Miyaura coupling in solution and on solid support
Autore:
Hanazawa, T; Wada, T; Masuda, T; Okamoto, S; Sato, F;
Indirizzi:
Tokyo Inst Technol, Dept Biomol Engn, Midori Ku, Yokohama, Kanagawa 2268501, Japan Tokyo Inst Technol Yokohama Kanagawa Japan 2268501 anagawa 2268501, Japan
Titolo Testata:
ORGANIC LETTERS
fascicolo: 24, volume: 3, anno: 2001,
pagine: 3975 - 3977
SICI:
1523-7060(20011129)3:24<3975:NSAT1A>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
OPTICALLY-ACTIVE 5-(TERT-BUTYLDIMETHYLSILOXY)-2-CYCLOHEXENONE; VITAMIN-D; A-RING; 1-ALPHA,25-DIHYDROXYVITAMIN D-3; ASYMMETRIC-SYNTHESIS; PRACTICAL SYNTHESIS; BIOLOGICAL-ACTIVITY; ANALOGS; EFFICIENT; SYNTHON;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Sato, F Tokyo Inst Technol, Dept Biomol Engn, Midori Ku, 4259 Nagatsuta Cho, Yokohama, Kanagawa 2268501, Japan Tokyo Inst Technol 4259 Nagatsuta Cho Yokohama Kanagawa Japan 2268501
Citazione:
T. Hanazawa et al., "Novel synthetic approach to 19-nor-1 alpha,25-dihydroxyvitamin D-3 and itsderivatives by Suzuki-Miyaura coupling in solution and on solid support", ORG LETT, 3(24), 2001, pp. 3975-3977

Abstract

[GRAPHICS]19-nor-1 alpha ,25-Dihydroxyvitamin D-3 was synthesized by the Suzuki-Miyaura coupling of the A-ring intermediate 3, which was efficiently prepared from readily available 5-(tert butyldimethylsilyl)oxycyclohex-2-enone (5), with the boronate compound of the C,D-ring portion. The method could be applied to a solid-phase synthesis to prepare the des-C,D derivatives of 19-nor-1 alpha ,25-dihydroxyvitamin D-3.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:59:52